Evidence map›Paper›PMID 27339075›Full record

ArticleJournal of the American Society of Hypertension : JASH2016

Hypertension and alterations in left ventricular structure and geometry in African Americans: the Jackson Heart Study.

Marwah Abdalla, John N Booth, Keith M Diaz, Mario Sims, Paul Muntner, Daichi Shimbo

Abstract read
In one paragraph

Article in Journal of the American Society of Hypertension : JASH, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Predictive value of incidental right ventricular abnormalities identified on SPECT for mortality and pulmonary hypertension.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  3. Article
  4. Article
  5. Preserved endothelial progenitor cell angiogenic activity in African American essential hypertensive patients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2018
    Article
  6. Blood Pressure Variability and Cognitive Function Among Older African Americans: Introducing a New Blood Pressure Variability Measure.Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2017
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marwah AbdallaDepartment of Medicine, Columbia University Medical Center, New York, NY, USA. Electronic address: ma2947@cumc.columbia.edu.
John N BoothDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Keith M DiazDepartment of Medicine, Columbia University Medical Center, New York, NY, USA.
Mario SimsDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Daichi ShimboDepartment of Medicine, Columbia University Medical Center, New York, NY, USA.

Funding

WORKSITE BLOOD PRESSURE STUDYP01HL047540 · NHLBI · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI SCHWARTZ, JOSEPH E · 1993 to 2014
$27.7M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
UAB Diabetes Research and Training CenterP60DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GARVEY, W TIMOTHY · 2008 to 2012
$8.4M
Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
JACKSON HEART STUDY--EXAM CENTERN01HC095171 · HC · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI JONES, DANIEL W · 1999 to 2001
$4.6M
Midcareer Investigator Award in Patient-Oriented Research in Human HypertensionK24HL125704 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2015 to 2019
$573k
JACKSON HEART STUDY--TRAINING CENTERN01HC095172 · HC · TOUGALOO COLLEGE · PI SRINIVASAN, ASOKA · 1999 to 2001
$516k
Development of a humanized anti-CD47 antibody for treatment of tissue ischemia.R41HL095172 · NHLBI · VASCULOX, INC. · PI FRAZIER, WILLIAM A · 2009 to 2009
$198k
JACKSON HEART STUDY-N01HC95170N01HC095170 · HC · JACKSON STATE UNIVERSITY · PI TAYLOR, HERMAN ALFRED · 1999 to 2006
$20k
NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201300048CNHLBI NIH HHS HHSN268201300049CNHLBI NIH HHS HHSN268201300050CNHLBI NIH HHS K24 HL125704NHLBI NIH HHS N01 HC095170NHLBI NIH HHS N01 HC095171NHLBI NIH HHS N01 HC095172NHLBI NIH HHS P01 HL047540NHLBI NIH HHS R01 HL117323NIDDK NIH HHS P60 DK079626
6 · The paper itself

Abstract

African Americans (AAs) have an increased risk for hypertension-related cardiovascular outcomes compared with whites, which may be related to abnormal left ventricular (LV) structure. We examined the association of prevalent hypertension with concentric remodeling (CR; normal LV mass index [LVMI] and increased relative wall thickness [RWT]), eccentric hypertrophy (increased LVMI and normal RWT), and concentric hypertrophy (CH; increased LVMI and increased RWT) within the Jackson Heart Study. Among 4721 participants (mean ± SD, age 55.7 ± 12.7 years), 2841 (60.2%) had prevalent hypertension, defined as mean clinic blood pressure ≥140/90 mm Hg or antihypertensive medication use. Prevalent hypertension was associated with a statistically significantly increased odds for having CR (odds ratio [OR] = 1.78, 95% confidence interval [CI] = 1.42-2.24), eccentric hypertrophy (OR = 1.68; 95% CI = 1.15-2.44), and CH (OR = 3.86, 95% CI = 2.28-6.54) after multivariable adjustment. In conclusion, in a population-based sample of AAs, hypertension was associated with increased odds for having abnormal LV structure, particularly CH.

Indexed as

Ventricular RemodelingAdultAgedAntihypertensive AgentsBlack or African AmericanBlood PressureCohort StudiesEchocardiographyFemaleHeart VentriclesHumansHypertensionHypertrophy, Left VentricularMaleMiddle AgedPrevalenceAntihypertensive AgentsEchocardiography

Identifiers

PMID27339075
PMCPMC4958512

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.