ArticleRadiation oncology (London, England)2016
The effect of extremely narrow MLC leaf width on the plan quality of VMAT for prostate cancer.
Article in Radiation oncology (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Spiral volumetric modulated arc therapy for whole-brain radiotherapy with simultaneous integrated boost to multiple brain metastases.Radiation oncology (London, England) · 2025Article
- Two-dimensional dynamic multileaf collimator (2DDMLC) technique for improved treatment quality in intensity modulated radiation therapy.Scientific reports · 2025Article
- Effect of the simulated half leaf width of a multileaf collimator on volumetric modulated arc therapy plan quality in hippocampal avoidance whole-brain radiotherapy.Journal of applied clinical medical physics · 2022Article
- Dosimetric sensitivity of leaf width on volumetric modulated arc therapy plan quality: an objective approach.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022Article
- Investigation of optimum minimum segment width on VMAT plan quality and deliverability: A comprehensive dosimetric and clinical evaluation using DVH analysis.Journal of applied clinical medical physics · 2021Article
- Is High Definition MLC Dosimetrically Superior to Standard Definition MLC for SIB-SBRT for Carcinoma Prostate.Asian Pacific journal of cancer prevention : APJCP · 2019Article
- Comparison of treatment plans between IMRT with MR-linac and VMAT for lung SABR.Radiation oncology (London, England) · 2019Article
- Treatment plan comparison between Tri-Co-60 magnetic-resonance image-guided radiation therapy and volumetric modulated arc therapy for prostate cancer.Oncotarget · 2017Article
- Quality of tri-Co-60 MR-IGRT treatment plans in comparison with VMAT treatment plans for spine SABR.The British journal of radiology · 2017Article
- Validation of Dosimetric Leaf Gap (DLG) prior to its implementation in Treatment Planning System (TPS): TrueBeam™ millennium 120 leaf MLC.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation OncologyArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the effect of multi-leaf collimators (MLCs) with leaf width of 1.25 mm on the plan quality of volumetric modulated arc therapy (VMAT) for prostate cancer.
methodsA total of 20 patients with prostate cancer were retrospectively selected. Using a high definition MLC (HD MLC), primary and boost VMAT plans with two full arcs were generated for each patient (original plan). After that, by shifting the isocenter position of the 2nd arc by 1.25 mm in the cranio-caudal direction, we simulated fluences made with MLCs with leaf width of 1.25 mm. After shifting, primary and boost plans were generated for each patient (shifted plan). A sum plan was generated by summation of the primary and boost plan for each patient. Dose-volumetric parameters were calculated and compared.
resultsBoth the homogeneity index (HI) and conformity index (CI) of the shifted plans were better than those of the original plans in primary plans (HI = 0.065 vs. 0.059 with p < 0.001 and CI = 1.056 vs. 1.044 with p = 0.006). Similarly, the shifted plans for the boost target volume showed better homogeneity and conformity than did the original plans (HI = 0.060 vs. 0.053 with p < 0.001 and CI = 1.015 vs. 1.009 with p < 0.001). The target mean dose of the original plans was closer to the prescription dose than that of the shifted plans in the case of sum plans (81.45 Gy vs. 81.12 Gy with p = 0.001).
conclusionsUse of extremely narrow MLCs could increase dose homogeneity and conformity of the target volume for prostate VMAT.
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