ArticleScientific reports2016
Photo-derived transformation from modified chitosan@calcium carbonate nanohybrids to nanosponges.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed, 11 citations in OpenAlex.
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1 author at 1 institution in 1 country.
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Abstract
Zwitterionic chitosan (ZC)@calcium carbonate (CC) nanoparticles were conveniently obtained and transformed to biocompatible nanosponges by continuous gas-phase photo-derived transformation in a single-pass configuration, and their potential use for biomedical applications was investigated. The mean diameter of the ZC@CC sponges was ~166 nm (~72 nm for CC and, ~171 nm for ZC), and the sponges had a mesoporous structure (i.e., an average pore diameter of ~13 nm). Measurements of the sponge cytotoxicity were performed and only a slight decrease was observed (>78% in cell viability) when compared with pure ZC (>80%). The ZC@CC sponges had a similar transfection ability to lipofectamine (~2.7 × 10(9) RLU mg(-1) protein) at a 50:1 ratio of sponge:DNA weight. Because of a porous structure, the sponges showed remarkably higher transfection efficiencies than pure ZC.
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