Evidence map›Paper›PMID 27338804›Full record

SynthesisAddiction (Abingdon, England)2016

Behavioural tasks sensitive to acute abstinence and predictive of smoking cessation success: a systematic review and meta-analysis.

Meryem Grabski, H Valerie Curran, David J Nutt, Stephen M Husbands, Tom P Freeman, Meg Fluharty, Marcus R Munafò

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Addiction (Abingdon, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Cigarette smoking is associated with reduced neuroinflammation and better cognitive control in people living with HIV.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  4. Article
  5. Article
  6. Affect and subjective cognitive functioning by depression symptom levels during naturalistic cigarette smoking in premenopausal females who smoke daily.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2022
    Article
  7. Article
  8. Article
  9. Cognitive rigidity and BDNF-mediated frontostriatal glutamate neuroadaptations during spontaneous nicotine withdrawal.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. No Effect of Commercial Cognitive Training on Brain Activity, Choice Behavior, or Cognitive Performance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Meryem GrabskiSchool of Experimental Psychology, University of Bristol, Bristol, UK.
H Valerie CurranClinical Psychopharmacology Unit, University College London, London, UK.
David J NuttDepartment of Medicine, Imperial College London, London, UK.
Stephen M HusbandsDepartment of Pharmacy and Pharmacology, University of Bath, Bath, UK.
Tom P FreemanClinical Psychopharmacology Unit, University College London, London, UK.ORCID 0000-0002-5667-507X
Meg FluhartySchool of Experimental Psychology, University of Bristol, Bristol, UK.
Marcus R MunafòSchool of Experimental Psychology, University of Bristol, Bristol, UK.
University of Bristol · GBUniversity College London · GBImperial College London · GBUniversity of Bath · GB

Funding

British Heart FoundationCancer Research UKMedical Research Council MC_UU_12013/6Medical Research Council MR/K023195/1
6 · The paper itself

Abstract

BACKGROUND AND

aimsPerformance on cognitive tasks may be sensitive to acute smoking abstinence and may also predict whether quit attempts fail. Our aim was to conduct a systematic review and meta-analysis to identify cognitive tasks sensitive to acute abstinence and predictive of smoking cessation success.

methodsEmbase, Medline, PsycInfo and Web of Science were searched up to March 2016. Studies were included if they enrolled adults and assessed smoking using a quantitative measure. Studies were combined in a random effects meta-analysis.

resultsWe included 42 acute abstinence studies and 13 cessation studies. There was evidence for an effect of abstinence on delay discounting [d = 0.26, 95% confidence interval (CI) = 0.07-0.45, P = 0.005], response inhibition (d = 0.48, 95% CI = 0.26-0.70, P < 0.001), mental arithmetic (d = 0.38, 95% CI = 0.06-0.70, P = 0.018), and recognition memory (d = 0.46, 95% CI = 0.23-0.70, P < 0.001). In contrast, performance on the Stroop (d = 0 .17, 95% CI = -0.17-0.51, P = 0.333) and smoking Stroop (d = 0.03, 95% CI = -0.11-0.17, P = 0.675) task was not influenced by abstinence. We found only weak evidence for an effect of acute abstinence on dot probe task performance (d = 0.15, 95% CI = -0.01-0.32, P = 0.072). The design of the cessation studies was too heterogeneous to permit meta-analysis.

conclusionsCompared with satiated smokers, acutely abstinent smokers display higher delay discounting, lower response inhibition, impaired arithmetic and recognition memory performance. However, reaction-time measures of cognitive bias appear to be unaffected by acute tobacco abstinence. Conclusions about cognitive tasks that predict smoking cessation success were limited by methodological inconsistencies.

Indexed as

AdultCognitive Behavioral TherapyFemaleHumansMalePsychomotor PerformanceRecurrenceSample SizeSmoking CessationTreatment OutcomeAbstinencecessationcognitionmeta-analysisperformancesmokingsystematic reviewtobacco

Identifiers

PMID27338804
PMCPMC5111768
OpenAlexW2463217744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.