ArticleScience (New York, N.Y.)2016
Aryl amination using ligand-free Ni(II) salts and photoredox catalysis.
Article in Science (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
122 citing papers in PubMed, 615 citations in OpenAlex.
- Pyrimidine-Mediated Electronic Modulation of Ionic Carbon Nitrides for Green Light-Driven Photocatalysis.ACS materials Au · 2026Article
- Base-Free C-N Cross-Electrophile Coupling.Journal of the American Chemical Society · 2026Article
- Metal-Centered Photoredox Catalysis using d6 Transition Metal-based Chromophores.Accounts of chemical research · 2026Article
- From reagents to feedstocks: reprogramming heteroatom-containing molecules in modern organic synthesis.Molecular diversity · 2026Review
- Tailoring polymers of intrinsic microporosity as photoredox catalysts for continuous-flow reaction-separation processes.Nature communications · 2026Article
- Cobalt-Catalyzed Highly Regioselective Alkoxycarbonylation of Olefins Driven by Light.Journal of the American Chemical Society · 2026Article
- Photochemical, electrochemical and electrophotochemical C-N bond-forming cross-coupling reactions.Nature reviews. Chemistry · 2026Review
- Advances in NiACS catalysis · 2026Review
- Nickel-Photochemical C-N Couplings: Moving Beyond Iridium Photocatalysts.Trends in chemistry · 2025Article
- Quantum Dots for Visible-Light-Driven Organic Transformations: a Chemist Perspective.Topics in current chemistry (Cham) · 2025Review
- Electrochemically promoted defluorinative sulfoximination and fluorosulfonylation of non-activated aryl fluorides at room temperature.Chemical science · 2025Article
- Advances in Copper and Nickel C─N and C─O Cross-Couplings of (Hetero)Aryl Chlorides Enabled by Ancillary Ligand Development.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Review
- Article
- Indole Photocatalysts and Secondary Amine Ligands Enable Nickel-Photoredox C(spACS catalysis · 2025Article
- Emerging Opportunities of Colloidal Quantum Dots for Photocatalytic Organic Transformations.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- A scalable photo-mechanochemical platform for sustainable photoredox catalysis by resonant acoustic mixing.Nature communications · 2025Article
- Recent synthetic strategies for N-arylation of pyrrolidines: a potential template for biologically active molecules.Molecular diversity · 2025Review
- Nickel-mediated aerobic C(sp2)-nucleophile coupling reactions for late-stage diversification of aryl electrophiles.Nature synthesis · 2025Article
- Cross-Coupling Reactions with Nickel, Visible Light, andACS catalysis · 2025Article
- Emerging trends in the optimization of organic synthesis through high-throughput tools and machine learning.Beilstein journal of organic chemistry · 2025Review
62 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Over the past two decades, there have been major developments in transition metal-catalyzed aminations of aryl halides to form anilines, a common structure found in drug agents, natural product isolates, and fine chemicals. Many of these approaches have enabled highly efficient and selective coupling through the design of specialized ligands, which facilitate reductive elimination from a destabilized metal center. We postulated that a general and complementary method for carbon-nitrogen bond formation could be developed through the destabilization of a metal amido complex via photoredox catalysis, thus providing an alternative approach to the use of structurally complex ligand systems. Here, we report the development of a distinct mechanistic paradigm for aryl amination using ligand-free nickel(II) salts, in which facile reductive elimination from the nickel metal center is induced via a photoredox-catalyzed electron-transfer event.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.