ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2016
Hypophosphatemia promotes lower rates of muscle ATP synthesis.
Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04146935 (Examining the Effect of Burosumab on Muscle Function Using MR Spectroscopy), which is not on this map. Cited by 64 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Examining the Effect of Burosumab on Muscle Function Using MR Spectroscopy
Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.
- Pooled it
- Trial
- Patient-Reported Outcomes from a Randomized, Active-Controlled, Open-Label, Phase 3 Trial of Burosumab Versus Conventional Therapy in Children with X-Linked Hypophosphatemia.Calcified tissue international · 2021Trial
- Peripartum hypophosphatemia is associated with a hindgut-centered microbiota-metabolite-host axis in transition dairy cows.NPJ biofilms and microbiomes · 2026Article
- ELECTROHEALTH study: prevalence and prognostic significance of mild hypophosphatemia in older adults.Aging clinical and experimental research · 2026Article
- Development of a severe rat refeeding syndrome model and mathematical modeling of the associated hypophosphatemia.NPJ systems biology and applications · 2026Article
- The impact of hyperparathyroidism on skeletal muscle pathophysiology and physical function.Endocrine connections · 2026Review
- Phosphorus Metabolism and Function in Ruminants: Current Knowledge.Animals : an open access journal from MDPI · 2026Review
- Supplements for bone health.Archives of endocrinology and metabolism · 2025Review
- Growth dynamics of transversal body dimensions and proportions, with related clinical determinants in children with X-linked hypophosphatemia treated with phosphate supplements and active vitamin D.Pediatric nephrology (Berlin, Germany) · 2025Observational
- Correlation Between Hypophosphatemia and Hyperventilation in Critically Ill Patients: Causes, Clinical Manifestations, and Management Strategies.Biomedicines · 2025Review
- X-Linked Hypophosphatemia: Role of Fibroblast Growth Factor 23 on Human Skeletal Muscle-Derived Cells.Calcified tissue international · 2025Article
- Article
- Risk Factors and Predictive Models for Sarcopenia in Older Adults.Aging medicine (Milton (N.S.W)) · 2025Article
- The inverse relation between changes in body weight and serum phosphate expresses weight loss after lifestyle intervention in non-smokers and smokers, but not in subjects who quit smoking.Frontiers in nutrition · 2025Article
- Article
- Article
- Skeletal Muscle Injury in Chronic Kidney Disease-From Histologic Changes to Molecular Mechanisms and to Novel Therapies.International journal of molecular sciences · 2024Review
- Effect of Burosumab on Muscle Function and Strength, and Rates of ATP Synthesis in Skeletal Muscle in Adults With XLH.The Journal of clinical endocrinology and metabolism · 2024Article
- Phosphaturic mesenchymal tumor of the popliteal fossa: a case report and literature review.Frontiers in oncology · 2024Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 2 countries.
Funding
Abstract
Hypophosphatemia can lead to muscle weakness and respiratory and heart failure, but the mechanism is unknown. To address this question, we noninvasively assessed rates of muscle ATP synthesis in hypophosphatemic mice by using in vivo saturation transfer [
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.