ArticlePediatrics2016
Validation of the Pittsburgh Infant Brain Injury Score for Abusive Head Trauma.
Article in Pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 83 citations in OpenAlex.
- Medical findings in young patients with head trauma: How strong is the evidence for abuse?International journal of legal medicine · 2026Article
- Prior Head Circumference Measurements in Infants With Older Subdural Hematomas: Did We Miss It?Clinical pediatrics · 2026Article
- Subconjunctival Hemorrhages Are Rare Among Infants With Cough and Gastrointestinal Conditions.Pediatric emergency care · 2025Article
- Evaluation of a Child Abuse Screen Performed by Nurses Among Young Children with Fractures Seen in a Pediatric Emergency Department.Rhode Island medical journal (2013) · 2024Observational
- Identification and Evaluation of Non-Accidental Trauma in the Pediatric Population: A Clinical Review.Children (Basel, Switzerland) · 2024Review
- Development, contributions, and future directions of a multicenter child abuse research network.Current problems in pediatric and adolescent health care · 2024Article
- Diagnosis of Abusive Head Trauma : Neurosurgical Perspective.Journal of Korean Neurosurgical Society · 2022Article
- Screening for pediatric abusive head trauma: Are three variables enough?Child abuse & neglect · 2022Article
- A Cluster Randomized Trial to Reduce Missed Abusive Head Trauma in Pediatric Intensive Care Settings.The Journal of pediatrics · 2021Article
- Validation of a Clinical Decision Rule to Predict Abuse in Young Children Based on Bruising Characteristics.JAMA network open · 2021Observational
- Neuroendoscopic Approach of a Massive Bilateral Chronic Subdural Hematoma in a Child Using a Single Burr Hole.Cureus · 2021Article
- A natural language processing and deep learning approach to identify child abuse from pediatric electronic medical records.PloS one · 2021Article
- Neuroimaging in Pediatric Patients with Mild Traumatic Brain Injury: Relating the Current 2018 Centers for Disease Control Guideline and the Potential of Advanced Neuroimaging Modalities for Research and Clinical Biomarker Development.Journal of neurotrauma · 2021Review
- Identification of Abusive Head Trauma in High-Risk Infants: A Cost-Effectiveness Analysis.The Journal of pediatrics · 2020Article
- Pediatric abusive head trauma.Biomedical journal · 2020Review
- Advances and Future Directions of Diagnosis and Management of Pediatric Abusive Head Trauma: A Review of the Literature.Frontiers in neurology · 2020Review
- Estimating the probability of abusive head trauma after abuse evaluation.Child abuse & neglect · 2019Article
- The "New Science" of Abusive Head Trauma.International journal on child maltreatment : research, policy and practice · 2019Article
- Occult head injury is common in children with concern for physical abuse.Pediatric radiology · 2018Observational
- Development of an electronic medical record-based child physical abuse alert system.Journal of the American Medical Informatics Association : JAMIA · 2018Article
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Authors and funding
10 authors at 7 institutions in 1 country.
Funding
Abstract
backgroundAbusive head trauma is the leading cause of death from physical abuse. Misdiagnosis of abusive head trauma as well as other types of brain abnormalities in infants is common and contributes to increased morbidity and mortality. We previously derived the Pittsburgh Infant Brain Injury Score (PIBIS), a clinical prediction rule to assist physicians deciding which high-risk infants should undergo computed tomography of the head.
methodsWell-appearing infants 30 to 364 days of age with temperature <38.3°C, no history of trauma, and a symptom associated with an increased risk of having a brain abnormality were eligible for enrollment in this prospective, multicenter clinical prediction rule validation. By using a predefined neuroimaging paradigm, subjects were classified as cases or controls. The sensitivity, specificity, and negative and positive predictive values of the rule for prediction of brain injury were calculated.
resultsA total of 1040 infants were enrolled: 214 cases and 826 controls. The 5-point PIBIS included abnormality on dermatologic examination (2 points), age ≥3.0 months (1 point), head circumference >85th percentile (1 point), and serum hemoglobin <11.2g/dL (1 point). At a score of 2, the sensitivity and specificity for abnormal neuroimaging was 93.3% (95% confidence interval 89.0%-96.3%) and 53% (95% confidence interval 49.3%-57.1%), respectively.
conclusionsOur data suggest that the PIBIS accurately identifies infants who would benefit from neuroimaging to evaluate for brain injury. An implementation analysis is needed before the PIBIS can be integrated into clinical practice.
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