Evidence map›Paper›PMID 27338586›Full record

ArticleJournal of anatomy2016

Spatially dense morphometrics of craniofacial sexual dimorphism in 1-year-olds.

Harold Matthews, Tony Penington, Ine Saey, Jane Halliday, Evelyn Muggli, Peter Claes

Open access · bronzeAbstract read
In one paragraph

Article in Journal of anatomy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  6. Arcuate eminence distance to temporal bone outer table in the middle fossa repair of superior canal dehiscence.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  7. Article
  8. Sex Differences in Velopharyngeal Anatomy of 9- and 10-Year-Old Children.Journal of speech, language, and hearing research : JSLHR · 2023
    Article
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  10. Article
  11. Article
  12. Article
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  16. Facial masculinity does not appear to be a condition-dependent male ornament and does not reflect MHC heterozygosity in humans.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Harold MatthewsMurdoch Childrens Research Institute, Melbourne, Victoria, Australia.
Tony PeningtonMurdoch Childrens Research Institute, Melbourne, Victoria, Australia.
Ine SaeyDepartment of Electrical Engineering, KU Leuven, Leuven, Belgium.
Jane HallidayMurdoch Childrens Research Institute, Melbourne, Victoria, Australia.
Evelyn MuggliMurdoch Childrens Research Institute, Melbourne, Victoria, Australia.
Peter ClaesMurdoch Childrens Research Institute, Melbourne, Victoria, Australia.
University of Melbourne · AURoyal Children's Hospital · AUUniversitair Ziekenhuis Leuven · BEVIB-KU Leuven Center for Microbiology · BE

Funding

Medical Research Council 1011070
6 · The paper itself

Abstract

Recent advances in the field of geometric morphometrics allow for powerful statistical hypothesis testing for effects of biological and environmental variables on anatomical shape. This study used partial least-squares regression (PLSR) and the recently developed bootstrapped response-based imputation modelling (BRIM) algorithm to test for sexual dimorphism in the craniofacial shape of 1-year-old humans. We observed a recession of the forehead in boys relative to girls, and differences in the nose, consistent with adult dimorphism. Results also suggest that the degree to which individuals express dimorphic traits is continuous throughout the population. This is also seen in adult dimorphism but in 1-year-olds the amount of overlap between groups is much higher, indicating the strength of dimorphism between sexes is lower. Our results demonstrate early sexual dimorphism that is not attributable to the influx of sex hormones at puberty. This highlights the need to look at very early ontogeny for the origins of sexual dimorphism. We suggest that future work look at potential mediating effects of this early dimorphism on the later impact of puberty. The subtle shape differences we have detected, may also be applied to sexing fossilised crania. A common artefact in 3D images of faces of young children is that they often have their mouths open to varying degrees, introducing variability in the data unrelated to anatomy. We describe two PLSR-based methods of correcting this. These methods may facilitate surgical planning and assessment of young children based on 3D images.

Indexed as

Sex CharacteristicsAlgorithmsFaceFemaleHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalInfantLeast-Squares AnalysisMaleSkullcraniofacialinfantsmorphometricspartial least-squares regressionposesexual dimorphism

Identifiers

PMID27338586
PMCPMC5013066
OpenAlexW2475331565

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.