Evidence map›Paper›PMID 27338559›Full record

ArticleAddiction (Abingdon, England)2016

Developmental course of non-medical use of prescription drugs from adolescence to adulthood in the United States: national longitudinal data.

Sean Esteban McCabe, Deborah D Kloska, Philip Veliz, Justin Jager, John E Schulenberg

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  11. Article
  12. Prescription Drug Misuse: Taking a Lifespan Perspective.Substance abuse : research and treatment · 2020
    Review
  13. Prescription Drug Misuse: Sources of Controlled Medications in Adolescents.Journal of the American Academy of Child and Adolescent Psychiatry · 2019
    Article
  14. Observational
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sean Esteban McCabeSubstance Abuse Research Center and Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI, USA.
Deborah D KloskaInstitute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Philip VelizInstitute for Research on Women and Gender, University of Michigan, Ann Arbor, MI, USA.
Justin JagerT. Denny Sanford School of Social and Family Dynamics, Arizona State University, Tempe, AZ, USA.
John E SchulenbergInstitute for Social Research and Department of Psychology, University of Michigan, Ann Arbor, MI, USA.

Funding

Monitoring the Future: Drug Use & Lifestyles of American Youth (Supp1: Nicotine Pouch and E-cigarette Use Among US Adolescents: National Estimates of Brand Use and Flavor Preferences)R01DA001411 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Richard A Miech · 1985 to 2026
$144.9M
Monitoring the Future: A Cohort-Sequential Panel Study of Drug Use, Ages 19-65 - Diversity Supplement (Solberg)R01DA016575 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Megan E. Patrick · 2003 to 2026
$44.6M
Trajectories of Prescription Nonmedical Drug MisuseR01DA031160 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEAN ESTEBAN MCCABE · 2011 to 2026
$3.7M
Longitudinal Changes in Recovery from Drug Use Disorders: A National StudyR01DA036541 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCCABE, SEAN ESTEBAN · 2015 to 2017
$647k
NIDA NIH HHS R01 DA001411NIDA NIH HHS R01 DA016575NIDA NIH HHS R01 DA031160NIDA NIH HHS R01 DA036541
6 · The paper itself

Abstract

aimsTo identify the developmental course of non-medical use of four separate prescription drug classes (opioids, sedatives, stimulants and tranquilizers) by examining the general functional growth and related covariates during the transition from adolescence to adulthood in the United States.

designNationally representative probability samples of high school seniors were followed longitudinally across five waves (waves 1, 2, 3, 4 and 5: modal ages 18, 19/20, 21/22, 23/24 and 25/26 years, respectively).

settingData were collected via self-administered questionnaires to high school seniors and young adults in the United States.

participantsThe sample consisted of nearly 72 000 individuals in 30 cohorts (high school senior years of 1977-2006) who participated in at least one wave. MEASUREMENTS: Self-reports of annual non-medical use of prescription opioids, sedatives, stimulants, and tranquilizers.

findingsThe annual non-medical use of prescription opioids, sedatives, stimulants and tranquilizers was highest at wave 1 over the five waves. There was a consistent descending path (linear and quadratic slopes, P < 0.001) in annual non-medical use from baseline across all four prescription drug classes (e.g. opioids linear slope = -0.043 and opioids quadratic slope = 0.034, P < 0.001). While the annual non-medical use of stimulants declined over time (linear slope = 0.063, P < 0.01; quadratic slope = -0.133, P < 0.001), the same decrease was not observed for the annual non-medical use of prescription opioids, sedatives or tranquilizers when controlling for socio-demographic and substance use behaviors at baseline. The covariates associated with the general functional growth differed across the four prescription drug classes.

conclusionsThe non-medical use of prescription opioids, sedatives, stimulants and tranquilizers appears to peak during late adolescence, suggesting preventive intervention efforts should be initiated in early adolescence. The developmental course of non-medical use is not the same among all four classes of prescription drugs, suggesting that each drug class warrants individual research.

Indexed as

Analgesics, OpioidCentral Nervous System StimulantsHypnotics and SedativesTranquilizing AgentsAdolescentAdultFemaleHumansLongitudinal StudiesMalePrescription Drug MisusePrevalenceSelf ReportUnited StatesYoung AdultAnalgesics, OpioidCentral Nervous System StimulantsHypnotics and SedativesTranquilizing AgentsAdolescencelongitudinalnon-medical useprescription drugsprescription opioidsprescription sedativesprescription stimulantsyoung adulthood

Identifiers

PMID27338559
PMCPMC5183528

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.