ArticleNutrients2016
Mother and Infant Body Mass Index, Breast Milk Leptin and Their Serum Leptin Values.
Article in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- The association between maternal factors and milk hormone concentrations: a systematic review.Frontiers in nutrition · 2024Pooled it
- Pooled it
- Association of Maternal Microbiota and Diet in Cord Blood Cytokine and Immunoglobulin Profiles.International journal of molecular sciences · 2021Trial
- Adolescent mothers' body composition and metabolic hormones (adiponectin, ghrelin, and leptin) in blood and human milk: associations with infant body composition.European journal of clinical nutrition · 2026Article
- The Association of Human Milk Appetite-Regulating Hormones with Infant Growth and Eating Behaviors to Age Six Months.Nutrients · 2026Article
- LEPR Contributes to Lung Squamous Cell Carcinoma: Insights From Mendelian Randomization and Experimental Studies.Cancer informatics · 2026Article
- Impact of Maternal Overweight and Obesity on Adipokines During Pregnancy and Lactation.International journal of molecular sciences · 2025Review
- Unravelling the effect of parity on immunoglobulins, cytokines and adipokines in human transitional milk and their association with infant infections during the first 6 months of life.International breastfeeding journal · 2025Article
- A comparative study on infant growth between assisted reproductive technology pregnancy and natural pregnancy.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Serum levels of leptin, ghrelin putative peptide YY-3 in patients with fetal alcohol spectrum disorders.Scientific reports · 2024Article
- Article
- Leptin and Leptin Receptor Polymorphisms in Infants and Their Parents: Correlation with Preterm Birth.Genes · 2024Article
- Understanding the Immunological Quality of Breast Milk in Maternal Overweight and Obesity.Nutrients · 2023Review
- A Diet Profiling Algorithm (DPA) to Rank Diet Quality Suitable to Implement in Digital Tools-A Test Study in a Cohort of Lactating Women.Nutrients · 2023Article
- Maternal Diet Influences Human Milk Protein Concentration and Adipose Tissue Marker.Nutrients · 2023Article
- Maternal inflammatory, lipid and metabolic markers and associations with birth and breastfeeding outcomes.Frontiers in nutrition · 2023Article
- Breast milk immune composition varies during the transition stage of lactation: characterization of immunotypes in the MAMI cohort.Frontiers in nutrition · 2023Article
- Leptin in Human Milk-One of the Key Regulators of Nutritional Programming.Molecules (Basel, Switzerland) · 2022Review
- Leptin Levels of the Perinatal Period Shape Offspring's Weight Trajectories through the First Year of Age.Nutrients · 2022Article
- Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study investigates correlations between mother and infant Body Mass Index (BMI), their serum leptin values and breast milk leptin concentration in early infancy. SUBJECTS AND
methodsWe determined serum leptin values in 58 healthy infants and leptin values in their mothers' breast milk, using radioimmunoassay (RIA). Infant and maternal anthropometrics were measured.
resultsMedian leptin concentration was 3.9 ng/mL (interquartile range (IQR): 2.75) in infant serum, 4.27 ng/mL (IQR: 5.62) in maternal serum and 0.89 ng/mL (IQR: 1.32) in breast milk. Median maternal BMI and weight were 24 kg/m² (IQR: 4.41) and 64 kg (IQR: 15). Median infant BMI was 15.80 kg/cm² (IQR: 4.02), while average weight was 5.130 kg (IQR: 1.627). Infants serum leptin values positively correlated with infants' BMI (p = 0.001; r = 0.213) and breast milk leptin (p = 0.03; r = 0.285). Maternal serum leptin values positively correlated with maternal BMI (p = 0.000, r = 0.449) and breast milk leptin ones (p = 0.026; r = 0.322).
conclusionBreast milk leptin and maternal BMI could influence infant serum leptin values. Further studies are needed to better elucidate the role of genetics and environment on infant leptin production and risk of obesity later in life.
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Registered trials
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