Evidence map›Paper›PMID 27338448›Full record

ReviewViruses2016

Marburg Virus Reverse Genetics Systems.

Kristina Maria Schmidt, Elke Mühlberger

Abstract readReview
In one paragraph

Review in Viruses, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Marburg Virus Disease: A Narrative Review.Health science reports · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
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  11. Review
  12. Review
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  14. Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kristina Maria SchmidtFriedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Novel and Emerging Infectious Diseases, Greifswald-Insel Riems 17493, Germany. kristina.schmidt@fli.bund.de.
Elke MühlbergerDepartment of Microbiology, School of Medicine, Boston University, 620 Albany Street, Boston, MA 02118, USA. muehlber@bu.edu.

Funding

National Center/Emerging Infectous Diseases &BiodefenseUC6AI058618 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MURPHY, JOHN R. · 2003 to 2006
$141.0M
Filovirus replication: initiation mechanism and role of RNA secondary structuresR03AI114293 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MUHLBERGER, ELKE C · 2014 to 2015
$164k
NIAID NIH HHS R03 AI114293NIAID NIH HHS UC6 AI058618
6 · The paper itself

Abstract

The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses. Reverse genetics systems established for MARV have been used to study various aspects of the viral replication cycle, analyze host responses, image viral infection, and screen for antivirals. This article provides an overview of the currently established MARV reverse genetic systems based on minigenomes, infectious virus-like particles and full-length clones, and the research that has been conducted using these systems.

Indexed as

MarburgvirusReverse GeneticsVirologybiosafety level 4Ebola virusfilovirusesfull-length clonesMarburg virusminigenomenonsegmented negative-sense RNA virusesreverse genetics systemvirus-like particlesvirus rescue

Identifiers

PMID27338448
PMCPMC4926198

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.