ReviewMicrobiology spectrum2016
Clostridium perfringens Sporulation and Sporulation-Associated Toxin Production.
Review in Microbiology spectrum, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 87 citations in OpenAlex.
- Complete genome sequence of Clostridium perfringens XZ-E1 isolated from yak feces in Xizang, China.BMC veterinary research · 2026Article
- Wastewater reuse for production of plant-based foods: does spore-formingApplied and environmental microbiology · 2026Review
- Seroprevalence, isolation, comprehensive characterization, and pathogenicity of Clostridium perfringens strain from yak in Xizang, China.Scientific reports · 2026Article
- Evolution of Translational Machinery in Fast- and Slow-Growing Bacteria.Microorganisms · 2026Article
- Type A and DFrontiers in cellular and infection microbiology · 2026Article
- Milestones in Clostridium perfringens research since 1995.Anaerobe · 2025Review
- Distribution and prevalence ofJournal of medical microbiology · 2025Article
- Genome MLST scheme for tracing genetic diversity and multidrug resistance of food animal-derivedCurrent research in food science · 2025Article
- The effect of culturing temperature on the growth of the most dominant bacterial species of human gut microbiota and harmful bacterial species.Bioscience of microbiota, food and health · 2025Article
- Unveiling the pathogenic mechanisms ofEmerging microbes & infections · 2024Review
- The effects of irrigation on the survival of3 Biotech · 2024Article
- The biology and pathogenicity ofMicrobiology and molecular biology reviews : MMBR · 2024Review
- Spores of Clostridioides difficile are toxin delivery vehicles.Communications biology · 2024Article
- High intestinal carriage ofMicrobiology spectrum · 2024Article
- Impact of pH and High-Pressure Pasteurization on the Germination and Development ofFoods (Basel, Switzerland) · 2024Article
- Review
- Overexpressing theToxins · 2024Article
- Review
- Identification of Germinants and Expression of Germination Genes inPathogens (Basel, Switzerland) · 2024Article
- Approaching pathogenicbioRxiv : the preprint server for biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
The ability of Clostridium perfringens to form spores plays a key role during the transmission of this Gram-positive bacterium to cause disease. Of particular note, the spores produced by food poisoning strains are often exceptionally resistant to food environment stresses such as heat, cold, and preservatives, which likely facilitates their survival in temperature-abused foods. The exceptional resistance properties of spores made by most type A food poisoning strains and some type C foodborne disease strains involve their production of a variant small acid-soluble protein-4 that binds more tightly to spore DNA than to the small acid-soluble protein-4 made by most other C. perfringens strains. Sporulation and germination by C. perfringens and Bacillus spp. share both similarities and differences. Finally, sporulation is essential for production of C. perfringens enterotoxin, which is responsible for the symptoms of C. perfringens type A food poisoning, the second most common bacterial foodborne disease in the United States. During this foodborne disease, C. perfringens is ingested with food and then, by using sporulation-specific alternate sigma factors, this bacterium sporulates and produces the enterotoxin in the intestines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.