Evidence map›Paper›PMID 27336707›Full record

ArticleNature protocols2016

MRI-guided stereotaxic brain surgery in the infant and adult common marmoset.

Inaki-Carril Mundinano, Paul A Flecknell, James A Bourne

Abstract read
PubMed Publisher
In one paragraph

Article in Nature protocols, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  7. Visual Cortical Area MT Is Required for Development of the Dorsal Stream and Associated Visuomotor Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
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  8. Article
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  10. Review
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  13. Applications of 3D printing in small animal magnetic resonance imaging.Journal of medical imaging (Bellingham, Wash.) · 2019
    Article
  14. Article
  15. Transient visual pathway critical for normal development of primate grasping behavior.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  16. Article
  17. Targeted Patching and Dendritic CaScientific reports · 2017
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Inaki-Carril MundinanoAustralian Regenerative Medicine Institute, Monash University, Clayton, Australia.
Paul A FlecknellComparative Biology Centre, Medical School, Newcastle University, Newcastle, UK.
James A BourneAustralian Regenerative Medicine Institute, Monash University, Clayton, Australia.ORCID 0000-0002-0902-3108
Australian Regenerative Medicine Institute · AUNewcastle University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past decade, the New World common marmoset (Callithrix jacchus) has taken a seminal position in neurobiological research, fueled in part by its smooth cortical sheet, which allows cortical areas to be easily accessed by current technologies on the dorsal surface of the brain. In this protocol, we describe a method for the precision placement of agents (e.g., tracers or neurotoxins) into small brain regions of the infant and adult marmoset, using an MRI-guided approach. This strategy uses a protocol for prolonged anesthesia without the need for intubation that we have recently developed, alongside appropriate analgesia and monitoring. The protocol can be readily adapted to be used together with advanced research techniques, such as two-photon microscopy and optical imaging. Including a 5-d postoperative care plan, this protocol takes 7 d to complete. The protocol requires a team of personnel experienced in marmoset care and handling, and small-animal neurosurgery; an assistant for monitoring the animal and assisting with anesthesia; and an MRI technician.

Indexed as

AnimalsAnimals, NewbornBrainCallithrixMagnetic Resonance ImagingModels, AnimalNeurosurgical ProceduresSurgery, Computer-Assisted

Identifiers

PMID27336707
OpenAlexW2460416055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.