Evidence map›Paper›PMID 27335858›Full record

ArticleISRN parasitology2013

Infectivity of Giardia duodenalis Cysts from UV Light-Disinfected Wastewater Effluent Using a Nude BALB/c Mouse Model.

Luciana Urbano Dos Santos, Delma Pegolo Alves, Ana Maria Aparecida Guaraldo, Romeu Cantusio Neto, Mauricio Durigan, Regina Maura Bueno Franco

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ISRN parasitology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Luciana Urbano Dos SantosLaboratory of Oxidation Processes, Department of Sanitation and Environment, School of Civil Engineering, Architecture and Urbanism, University of Campinas (UNICAMP), C.P. Box 6021, 13083-852 Campinas, SP, Brazil.
Delma Pegolo AlvesCEMIB Multidisciplinary Centre for Biological Investigation, University of Campinas (UNICAMP), C.P. Box 6095, 13083-877 Campinas, SP, Brazil.
Ana Maria Aparecida GuaraldoLaboratory of Helminthology, Department of Parasitology, Institute of Biology, University of Campinas (UNICAMP), C.P. Box 6109, 13083-970 Campinas, SP, Brazil.
Romeu Cantusio NetoLaboratory of Microbiology, Society for Water Supply and Sanitation (SANASA), Street Abolição 2.375, 13045-750 Campinas, SP, Brazil.
Mauricio DuriganLaboratory of Genetic and Molecular Analysis, Center of Molecular Biology and Genetic Engineering (CBMEG), Institute of Biology, University of Campinas (UNICAMP), C.P. Box 6109, 13083-875 Campinas, SP, Brazil.
Regina Maura Bueno FrancoLaboratory of Protozoology, Department of Animal Biology, Institute of Biology, University of Campinas (UNICAMP), C.P. Box 6109, 13083-970 Campinas, SP, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giardia duodenalis is a protozoan of public health interest that causes gastroenteritis in humans and other animals. In the city of Campinas in southeast Brazil, giardiasis is endemic, and this pathogen is detected at high concentrations in wastewater effluents, which are potential reservoirs for transmission. The Samambaia wastewater treatment plant (WWTP) in the city of Campinas employs an activated sludge system for sewage treatment and ultraviolet (UV) light for disinfection of effluents. To evaluate this disinfection process with respect to inactivating G. duodenalis cysts, two sample types were investigated: (i) effluent without UV disinfection (EFL) and (ii) effluent with UV disinfection (EFL+UV). Nude immunodeficient BALB/c mice were intragastrically inoculated with a mean dose of 14 cysts of G. duodenalis recovered from effluent from this WWTP, EFL, or EFL+UV. All animals inoculated with G. duodenalis cysts developed the infection, but animals inoculated with UV-exposed cysts released a lower average concentration of cysts in their faeces than animals inoculated with cysts that were not UV disinfected. Trophozoites were also observed in both groups of animals. These findings suggest that G. duodenalis cysts exposed to UV light were damaged but were still able to cause infection.

Identifiers

PMID27335858
PMCPMC4890921
OpenAlexW2041818759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.