Evidence map›Paper›PMID 27335709›Full record

ArticleCureus2016

Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection.

Katrina Chin-Loy, Farah Galaydh, Saad Shaikh

Erratum issuedOpen access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Katrina Chin-LoyOphthalmology, Howard University College of Medicine.
Farah GalaydhOphthalmology, Orlando Veterans Affairs Medical Center.
Saad ShaikhOphthalmology, UCF College of Medicine ; Ophthalmology, USF College of Medicine ; Ophthalmology, Howard University College of Medicine ; Ophthalmology, University of Texas Medical Branch at Galveston ; Ophthalmology, Orlando Veterans Affairs Medical Center ; Ophthalmology, Florida State University College of Medicine.
Howard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe report a case of retinopathy and uveitis associated with sofosbuvir therapy for hepatitis C infection.

methodsCase report.

resultsA 57-year-old-male developed ocular inflammation and retinopathy four weeks after the administration of sofosbuvir for a hepatitis C infection. Hearing loss, rheumatologic disease, and essential tremor were also noted. The ophthalmic findings resolved with discontinuation of the drug.

conclusionThe authors report a case of sofosbuvir induced retinopathy and uveitis, the first associated with this emerging therapy for hepatitis C. Ophthalmologists and other treating physicians should be aware of the ophthalmic side effects of this drug.

Indexed as

drugessential tremorretinopathyrheumatologysensorineural hearing losssofosbuvirtoxicityuveitis

Identifiers

PMID27335709
PMCPMC4895080
OpenAlexW2345374843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.