ArticleInternational journal of endocrinology and metabolism2016
Hypothyroidism and Lipid Levels in a Community Based Study (TTS).
Article in International journal of endocrinology and metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- Comparative efficacy of early morning versus bedtime administration of levothyroxine in children with hypothyroidism: a prospective, open label, randomized, case-control study.Pediatric endocrinology, diabetes, and metabolism · 2021Trial
- Study of Subclinical Hypothyroidism and its Association with Lipid Profile Among the Rural Population of Chamarajanagara District-A Hospital-Based Study.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2026Article
- Central hypothyroidism and cardiovascular disease: a Spanish cohort observational study.Hormones (Athens, Greece) · 2026Observational
- Hypothyroidism and Cardiovascular Disease: A Review.Cureus · 2024Review
- Comparative Study of Calculated LDL-Cholesterol Levels with the Direct Assay in Patients with Hypothyroidism.Journal of laboratory physicians · 2022Article
- Hypothyroidism correlates with dyslipidemia and protein contents in patients with various metabolic disorders.The Journal of international medical research · 2022Article
- Thyroid disorders and cardiovascular manifestations: an update.Endocrine · 2022Review
- gp91International journal of endocrinology · 2020Article
- Exercise training-induced changes in metabolic syndrome parameters, carotid wall thickness, and thyroid function in middle-aged women with subclinical hypothyroidism.Pflugers Archiv : European journal of physiology · 2019Article
- Thyroid function and ischemic heart disease: a Mendelian randomization study.Scientific reports · 2017Article
- Association of metabolic risks with subclinical hypothyroidism: A cross-sectional analysis.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThyroid hormones play an important role in lipid metabolism. Overt hypothyroidism is known to be associated with increased lipid profiles, but the effect of subclinical hypothyroidism (SCH) on lipid profile remains controversial.
objectivesThe aim of this study was to assess the association between thyroid disorders and serum lipid levels. MATERIALS AND
methodsThe present study was conducted within the framework of Tehran lipid and glucose study (TLGS). Serum concentrations of TSH and FT4, cholesterol, triglycerides and HDL-C were measured in 5786 randomly selected subjects. Serum LDL was calculated according to the Friedwald formula.
resultsThe study assessed 5154 subjects including 42.5% males and 57.5% females, with a mean age of 39.71 ± 14.2 years (ranged 20 - 90 years). Serum cholesterol was significantly higher in overt hypothyroidism in comparison to subclinical hypothyroidism (P = 0.003). Serum cholesterol, HDL -C, LDL-C and TG did not differ between subclinical hypothyroid and control groups. Among euthyroid men, serum FT4 levels were inversely correlated with serum cholesterol and TG. In euthyroid women, serum FT4 levels were correlated positively with serum HDL-C and negatively correlated with TG and TG/HDL-C ratio and TSH levels were associated negatively with, HDL-C.
conclusionsNo differences existed in lipid profiles between subclinical hypothyroidism and euthyroid subjects. There are correlations between serum FT4 and TSH and lipid profiles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.