Evidence map›Paper›PMID 27335567›Full record

ArticleNeural regeneration research2016

Repetitive magnetic stimulation affects the microenvironment of nerve regeneration and evoked potentials after spinal cord injury.

Jin-Lan Jiang, Xu-Dong Guo, Shu-Quan Zhang, Xin-Gang Wang, Shi-Feng Wu

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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  9. [Icariin alleviates lipid peroxidation after spinal cord injury in rats].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jin-Lan JiangScientific Research Center, China-Japan Union Hospital, Jilin University, Changchun, Jilin Province, China; Department of Orthopedics, China-Japan Union Hospital, Jilin University, Changchun, Jilin Province, China.
Xu-Dong GuoDepartment of Cardiovascular Medicine, China-Japan Union Hospital, Jilin University, Changchun, Jilin Province, China.
Shu-Quan ZhangDepartment of Orthopedics, Tianjin Nankai Hospital, Tianjin, China.
Xin-Gang WangDepartment of Burns and Plastic Surgery, China-Japan Union Hospital, Jilin University, Changchun, Jilin Province, China.
Shi-Feng WuDepartment of Burns and Plastic Surgery, China-Japan Union Hospital, Jilin University, Changchun, Jilin Province, China.ORCID 0000-0002-7326-3018
Jilin University · CNTianjin Nankai Hospital · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Repetitive magnetic stimulation has been shown to alter local blood flow of the brain, excite the corticospinal tract and muscle, and induce motor function recovery. We established a rat model of acute spinal cord injury using the modified Allen's method. After 4 hours of injury, rat models received repetitive magnetic stimulation, with a stimulus intensity of 35% maximum output intensity, 5-Hz frequency, 5 seconds for each sequence, and an interval of 2 minutes. This was repeated for a total of 10 sequences, once a day, 5 days in a week, for 2 consecutive weeks. After repetitive magnetic stimulation, the number of apoptotic cells decreased, matrix metalloproteinase 9/2 gene and protein expression decreased, nestin expression increased, somatosensory and motor-evoked potentials recovered, and motor function recovered in the injured spinal cord. These findings confirm that repetitive magnetic stimulation of the spinal cord improved the microenvironment of neural regeneration, reduced neuronal apoptosis, and induced neuroprotective and repair effects on the injured spinal cord.

Indexed as

motor functionnerve regenerationneural regenerationplasticityratsregenerative microenvironmentrehabilitationrepetitive magnetic stimulationspinal cord injury

Identifiers

PMID27335567
PMCPMC4904474
OpenAlexW2411599893

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.