Evidence map›Paper›PMID 27335372›Full record

ArticleAmerican journal of physiology. Renal physiology2016

Maintenance of vascular integrity by pericytes is essential for normal kidney function.

Dario R Lemos, Graham Marsh, Angela Huang, Gabriela Campanholle, Takahide Aburatani, Lan Dang, Ivan Gomez, Ken Fisher, Giovanni Ligresti, Janos Peti-Peterdi and 1 more

Abstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. The kidney stroma in development and disease.Nature reviews. Nephrology · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Toll-like Receptor 4 in Acute Kidney Injury.International journal of molecular sciences · 2023
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dario R LemosResearch and Development, Biogen, Cambridge, Massachusetts.
Graham MarshResearch and Development, Biogen, Cambridge, Massachusetts.
Angela HuangResearch and Development, Biogen, Cambridge, Massachusetts.
Gabriela CampanholleDivision of Nephrology, Department of Medicine, University of Washington, Seattle, Washington.
Takahide AburataniDivision of Nephrology, Department of Medicine, University of Washington, Seattle, Washington.
Lan DangResearch and Development, Biogen, Cambridge, Massachusetts.
Ivan GomezResearch and Development, Biogen, Cambridge, Massachusetts.
Ken FisherNortis Incorporated, Seattle, Washington; and.
Giovanni LigrestiResearch and Development, Biogen, Cambridge, Massachusetts.
Janos Peti-PeterdiDepartment of Physiology, University of Southern California, Los Angeles, California.
Jeremy S DuffieldResearch and Development, Biogen, Cambridge, Massachusetts; jeremy.duffield@biogen.com jeremysd@u.washington.edu.

Funding

Multiphoton Imaging of the Juxtaglomerular ApparatusR01DK064324 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JANOS PETI-PETERDI · 2004 to 2026
$8.4M
Novel imaging approach to study podocyte function in vivoR01DK100944 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PETI-PETERDI, JANOS · 2014 to 2017
$1.5M
Kidney Progenitor Cells in DiseaseR24DK094768 · NIDDK · UNIVERSITY OF WASHINGTON · PI GROSS, KENNETH W, PRUITT, STEVEN C · 2012 to 2012
$533k
NIDDK NIH HHS R01 DK064324NIDDK NIH HHS R01 DK100944NIDDK NIH HHS R24 DK094768
6 · The paper itself

Abstract

Pericytes are tissue-resident mesenchymal progenitor cells anatomically associated with the vasculature that have been shown to participate in tissue regeneration. Here, we tested the hypothesis that kidney pericytes, derived from FoxD1

Indexed as

Acute Kidney InjuryAnimalsCapillariesEndothelium, VascularKidneyMiceMice, TransgenicMicrovesselsPericytesPermeabilityacute kidney injuryendotheliummicrofluidicspericyte

Identifiers

PMID27335372
PMCPMC5210201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.