Evidence map›Paper›PMID 27335087›Full record

ArticleIntegrative cancer therapies2017

Fuzheng Qingjie Granules Inhibit Growth of Hepatoma Cells via Inducing Mitochondria-Mediated Apoptosis and Enhancing Immune Function.

Xuzheng Chen, Zhiyun Cao, Youquan Zhang, Jinnong Li, Suqing Wang, Jian Du, Lianming Liao

Open access · goldAbstract read
In one paragraph

Article in Integrative cancer therapies, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Exogenous melatonin mediates radish (Frontiers in plant science · 2023
    Article
  4. The potential of plant extracts in cell therapy.Stem cell research & therapy · 2022
    Review
  5. Review
  6. Effects of Chemotherapy on Hematological Parameters and CD4Animals : an open access journal from MDPI · 2022
    Article
  7. Article
  8. Review
  9. Review
  10. Using Traditional Chinese Medicine to Treat Hepatocellular Carcinoma by Targeting Tumor Immunity.Evidence-based complementary and alternative medicine : eCAM · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xuzheng Chen1 Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Zhiyun Cao1 Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Youquan Zhang1 Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Jinnong Li1 Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Suqing Wang2 Hospital of Fuzhou University, Fuzhou, People's Republic of China.
Jian Du1 Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Lianming Liao1 Fujian University of Traditional Chinese Medicine, Fuzhou, People's Republic of China.
Fujian University of Traditional Chinese Medicine · CNFuzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fuzheng Qingjie (FZQJ) granules, a compound Chinese medicine, have been used as an adjuvant therapy for alimentary tract cancers. However, the underlying anticancer mechanisms are still not well understood. In the present study, HepG2 cells were treated with FZQJ-containing serum. Cell proliferation was evaluated using MTT assay. Apoptosis was analyzed using a flow cytometer. Cell ultrastructure was observed under a transmission electron microscope. The mitochondrial membrane potential (Δψ) was examined with JC-1 dye. In H22 tumor-bearing mice, CD4

Indexed as

AnimalsAntineoplastic AgentsApoptosisbcl-2-Associated X ProteinCarcinoma, HepatocellularCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell Line, TumorCell ProliferationDrugs, Chinese HerbalHep G2 CellsHumansImmunityKiller Cells, NaturalLiverLiver NeoplasmsAntineoplastic Agentsbcl-2-Associated X ProteinDrugs, Chinese HerbalTumor Necrosis Factor-alphaapoptosisFuzheng Qingjie granuleshepatomaimmune functionmitochondrial membrane potential

Identifiers

PMID27335087
PMCPMC5759932
OpenAlexW2463376573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.