ArticleJournal of biomedical optics2016
Stimulus-evoked outer segment changes in rod photoreceptors.
Article in Journal of biomedical optics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed, 17 citations in OpenAlex.
- Functional OCT with parfocal retinal stimulation enables multi-site optoretinography under a single dark adaptation.Biomedical optics express · 2026Article
- Polarization optical coherence tomography optoretinography: verifying light-induced photoreceptor outer segment shrinkage and subretinal space expansion.Neurophotonics · 2025Article
- Volumetric data analysis enabled spatially resolved optoretinogram to measure the functional signals in the living retina.Journal of biophotonics · 2022Article
- Functional Optical Coherence Tomography for Intrinsic Signal Optoretinography: Recent Developments and Deployment Challenges.Frontiers in medicine · 2022Review
- Super-resolution ophthalmoscopy: Virtually structured detection for resolution improvement in retinal imaging.Experimental biology and medicine (Maywood, N.J.) · 2021Review
- Functional optical coherence tomography enablesBiomedical optics express · 2020Article
- Fast intrinsic optical signal correlates with activation phase of phototransduction in retinal photoreceptors.Experimental biology and medicine (Maywood, N.J.) · 2020Review
- Functional optical coherence tomography of neurovascular coupling interactions in the retina.Journal of biophotonics · 2018Article
- Functional optical coherence tomography of retinal photoreceptors.Experimental biology and medicine (Maywood, N.J.) · 2018Review
- Light-Induced Length Shrinkage of Rod Photoreceptor Outer Segments.Translational vision science & technology · 2018Article
- In vivo super-resolution imaging of transient retinal phototropism evoked by oblique light stimulation.Journal of biomedical optics · 2018Article
- Comparative investigation of stimulus-evoked rod outer segment movement and retinal electrophysiological activity.Proceedings of SPIE--the International Society for Optical Engineering · 2017Article
- Stimulus-evoked outer segment changes occur before the hyperpolarization of retinal photoreceptors.Biomedical optics express · 2017Article
- In vivo super-resolution retinal imaging through virtually structured detection.Journal of biomedical optics · 2016Article
- In vivo optical coherence tomography of stimulus-evoked intrinsic optical signals in mouse retinas.Journal of biomedical optics · 2016Article
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Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Rod-dominated transient retinal phototropism (TRP) has been recently observed in freshly isolated mouse and frog retinas. Comparative confocal microscopy and optical coherence tomography revealed that the TRP was predominantly elicited from the rod outer segment (OS). However, the biophysical mechanism of rod OS dynamics is still unknown. Mouse and frog retinal slices, which displayed a cross-section of retinal photoreceptors and other functional layers, were used to test the effect of light stimulation on rod OSs. Time-lapse microscopy revealed stimulus-evoked conformational changes of rod OSs. In the center of the stimulated region, the length of the rod OS shrunk, while in the peripheral region, the rod OS swung toward the center region. Our experimental observation and theoretical analysis suggest that the TRP may reflect unbalanced rod disc-shape changes due to localized visible light stimulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.