ArticleAnnals of surgical oncology2016
Current Trends in the Management of Phyllodes Tumors of the Breast.
Article in Annals of surgical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Management and Outcomes of Metastatic and Recurrent Malignant Phyllodes Tumors of the Breast: A Systematic Literature Review.European journal of breast health · 2023Pooled it
- Incidental colon adenocarcinoma in a patient with an Exophytic breast mass.Oxford medical case reports · 2026Article
- Adjuvant radiotherapy and survival in patients with malignant phyllode tumors: a population-based retrospective study.Breast cancer (Tokyo, Japan) · 2026Article
- The impact of adjuvant radiotherapy on borderline and malignant phyllodes tumors of the breast.Breast cancer (Tokyo, Japan) · 2025Article
- Phyllodes tumors of the breast: Real world data from a multi-institution cohort.Breast (Edinburgh, Scotland) · 2025Article
- Contemporary management of phyllodes tumours of the breast: recommendations from the UK Association of Breast Surgery.The British journal of surgery · 2025Article
- Surgical treatment of giant phyllodes tumors of the breast: a series of rare cases.Frontiers in oncology · 2025Article
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- Phyllodes Tumors of the Breast: Addressing the Gaps in Consensus Recommendations for Clinical Management.Annals of surgical oncology · 2023Article
- The phyllodes menace-Variation in course, therapy, and appearance of phyllodes tumors in a case series of three patients.Clinical case reports · 2023Article
- Clinical perspectives and outcomes of the giant breast phyllodes tumor and sarcoma: a real-world retrospective study.BMC cancer · 2023Article
- Current clinical practice in the management of phyllodes tumors of the breast: an international cross-sectional study among surgeons and oncologists.Breast cancer research and treatment · 2023Article
- Clinico-Pathological Factors Determining Recurrence of Phyllodes Tumors of the Breast: The 25-Year Experience at a Tertiary Cancer Centre.Journal of personalized medicine · 2023Article
- Margin Management and Adjuvant Therapy for Phyllodes Tumors: Practice Patterns of the American Society of Breast Surgeons Members.Annals of surgical oncology · 2022Article
- Malignant phyllodes tumor and primary breast sarcoma; distinct rare tumors of the breast.Journal of surgical oncology · 2022Article
- Apatinib treatment is effective for metastatic malignant phyllodes tumors of the breast: a case report.BMC women's health · 2021Article
- A Novel Breast-Conserving Surgical Technique in the Management of Phyllodes Tumours of the Breast.World journal of surgery · 2020Article
- A case of recurrent malignant phyllodes tumor undergoing nipple-sparing mastectomy with immediate breast reconstruction.Surgical case reports · 2020Article
- A giant malignant phyllodes tumor of breast post mastectomy with metastasis to stomach manifesting as anemia: a case report and review of literature.BMC surgery · 2020Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
introductionNational Comprehensive Cancer Network (NCCN) guidelines recommend wide excision without axillary staging to treat phyllodes tumors of the breast. Without prospective trials to guide management, NCCN also recommends consideration of radiation therapy (XRT). We describe current patterns of care for the multidisciplinary management of phyllodes tumors.
methodsUsing Surveillance, Epidemiology, and End Results Program (SEER) data, we identified women diagnosed with phyllodes tumors between 2000 and 2012 who underwent surgical therapy. Trends in breast-conserving surgery (BCS), nodal sampling, and XRT were assessed using the Cochrane-Armitage test. Multivariable logistic regression was used to identify factors associated with treatment.
resultsOf 1238 patients, 56.9 % underwent BCS and 23.6 % underwent nodal sampling (10.5 % after BCS vs. 40.9 % after mastectomy). After surgery, 15.4 % received adjuvant XRT (BCS 12.9 %, and mastectomy 18.8 %). XRT utilization increased significantly over the study period (BCS, p = < 0.0001; mastectomy, p = 0.0003), while nodal sampling did not change significantly. Women were more likely to receive mastectomy if they were older or had larger tumors. Nodal sampling was also associated with older age, larger tumor size, and receipt of mastectomy. Receipt of XRT was associated with later year of diagnosis, larger tumors, and nodal assessment.
conclusionOver time, an increasing number of women received XRT after surgical management of phyllodes tumor, and one in four women underwent nodal sampling. While some of this practice can be attributed to concern about more advanced disease in the absence of strong data, there may be an educational gap regarding current guidelines and appropriate management.
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