ArticleHypertension research : official journal of the Japanese Society of Hypertension2016
Estimation methods for human circadian phase by use of peripheral tissues.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Maternal circadian disruption during pregnancy and offspring diabetic cardiovascular disease risk.Frontiers in cell and developmental biology · 2026Review
- Hair Follicles as a Critical Model for Monitoring the Circadian Clock.International journal of molecular sciences · 2023Review
- Chronoradiobiology of Breast Cancer: The Time Is Now to Link Circadian Rhythm and Radiation Biology.International journal of molecular sciences · 2022Review
- The circadian clock and diseases of the skin.FEBS letters · 2021Review
- Acute kidney injury due to COVID-19 and the circadian rhythm.Medical hypotheses · 2021Review
- Identification of Clock Genes Related to Hypertension in Kidney From Spontaneously Hypertensive Rats.American journal of hypertension · 2020Article
- Bright light improves sleep in patients with Parkinson's disease: possible role of circadian restoration.Scientific reports · 2020Article
- Circadian Rhythms, Exercise, and Cardiovascular Health.Journal of circadian rhythms · 2018Review
- Effect of Melatonin on the Renin-Angiotensin-Aldosterone System in l-NAME-Induced Hypertension.Molecules (Basel, Switzerland) · 2018Article
- Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas.Cellular and molecular life sciences : CMLS · 2017Review
- Circadian rhythm of blood pressure and the renin-angiotensin system in the kidney.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Almost all living organisms, including humans, exhibit diurnal rhythms of physiology and behavior, which are driven by the circadian clock. Many studies have found that chronic misalignment between circadian and environmental/social rhythms carries a significant risk of various disorders, including sleep disorders, metabolic syndrome, cardiovascular diseases and cancer. However, irregular sleep-wake cycles and circadian maladjustment often cause 'social jet lag', which is minor but chronic jet-lag in our daily lives. Establishment of objective and convenient circadian-phase estimation methods in the clinical setting would therefore greatly contribute not only to resolving this global health problem but also to developing chronomedicine, a clinical approach for optimizing the time of day of treatments. Traditional melatonin-based methods have limitations with respect to circadian-phase evaluation; however, estimation methods based on clock gene expression may be able to compensate for these limitations. As a representative application of circadian-phase estimation based on clock gene expression, our method of using hair follicle cells may aid in the rapid clinical detection of circadian-related sleep problems, especially circadian rhythm sleep disorders that are masked because of forced adaptation to social time schedules.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.