Evidence map›Paper›PMID 27333914›Full record

ArticleThe Journal of infectious diseases2016

Ebola Laboratory Response at the Eternal Love Winning Africa Campus, Monrovia, Liberia, 2014-2015.

Emmie de Wit, Kyle Rosenke, Robert J Fischer, Andrea Marzi, Joseph Prescott, Trenton Bushmaker, Neeltje van Doremalen, Shannon L Emery, Darryl Falzarano, Friederike Feldmann and 27 more

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Pathogens (Basel, Switzerland) · 2020
    Article
  15. Article
  16. Article
  17. Long-term wildlife mortality surveillance in northern Congo: a model for the detection of Ebola virus disease epizootics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Emmie de WitLaboratory of Virology.
Kyle RosenkeLaboratory of Virology.
Robert J FischerLaboratory of Virology.
Andrea MarziLaboratory of Virology.
Joseph PrescottLaboratory of Virology.
Trenton BushmakerLaboratory of Virology.
Neeltje van DoremalenLaboratory of Virology.
Shannon L EmeryCenters for Disease Control and Prevention, Atlanta, Georgia.
Darryl FalzaranoLaboratory of Virology.
Friederike FeldmannRocky Mountain Veterinary Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana.
Allison GrosethLaboratory of Virology.
Thomas HoenenLaboratory of Virology.
Bonventure JumaCenter for Global Health, Division of Global Health Protection, Centers for Disease Control and Prevention.
Kristin L McNallyLaboratory of Virology.
Melvin OchiengKenya Medical Research Institute, Center for Global Health Research, Nairobi.
Victor OmballaKenya Medical Research Institute, Center for Global Health Research, Nairobi.
Clayton O OnyangoCenter for Global Health, Division of Global Health Protection, Centers for Disease Control and Prevention.
Collins OwuorKenya Medical Research Institute, Center for Global Health Research, Nairobi.
Thomas RoweCenters for Disease Control and Prevention, Atlanta, Georgia.
David SafronetzLaboratory of Virology.
Joshua SelfCenters for Disease Control and Prevention, Atlanta, Georgia.
Brandi N WilliamsonLaboratory of Virology.
Galina ZemtsovaCenters for Disease Control and Prevention, Atlanta, Georgia.
Allen GrollaSpecial Pathogens Program, Public Health Agency of Canada, Winnipeg.
Gary KobingerSpecial Pathogens Program, Public Health Agency of Canada, Winnipeg.
Mark RayfieldCenters for Disease Control and Prevention, Atlanta, Georgia.
Ute StröherCenters for Disease Control and Prevention, Atlanta, Georgia.
James E StrongSpecial Pathogens Program, Public Health Agency of Canada, Winnipeg.
Sonja M BestLaboratory of Virology.
Hideki EbiharaLaboratory of Virology.
Kathryn C ZoonCytokine Biology Section, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Stuart T NicholCenters for Disease Control and Prevention, Atlanta, Georgia.
Tolbert G NyenswahMinistry of Health and Social Welfare, Monrovia.
Fatorma K BolayLiberian Institute for Biomedical Research, Charlesville, Liberia.
Moses MassaquoiMinistry of Health and Social Welfare, Monrovia.
Heinz FeldmannLaboratory of Virology.
Barry FieldsCenter for Global Health, Division of Global Health Protection, Centers for Disease Control and Prevention.

Funding

Viral Hemorrhagic Fevers: Disease Modeling and TransmissionZIAAI001089 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI FELDMANN, HEINRICH · 2009 to 2025
$50.7M
Virus-Host Interactions: Induction and Evasion of Host Innate ImmunityZIAAI001125 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BEST, SONJA · 2010 to 2025
$28.1M
The Antiviral Activities of Human InterferonsZIAAI001039 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ZOON, KATHRYN · 2009 to 2016
$4.3M
6 · The paper itself

Abstract

West Africa experienced the first epidemic of Ebola virus infection, with by far the greatest number of cases in Guinea, Sierra Leone, and Liberia. The unprecedented epidemic triggered an unparalleled response, including the deployment of multiple Ebola treatment units and mobile/field diagnostic laboratories. The National Institute of Allergy and Infectious Diseases and the Centers for Disease Control and Prevention deployed a joint laboratory to Monrovia, Liberia, in August 2014 to support the newly founded Ebola treatment unit at the Eternal Love Winning Africa (ELWA) campus. The laboratory operated initially out of a tent structure but quickly moved into a fixed-wall building owing to severe weather conditions, the need for increased security, and the high sample volume. Until May 2015, when the laboratory closed, the site handled close to 6000 clinical specimens for Ebola virus diagnosis and supported the medical staff in case patient management. Laboratory operation and safety, as well as Ebola virus diagnostic assays, are described and discussed; in addition, lessons learned for future deployments are reviewed.

Indexed as

Africa, WesternCenters for Disease Control and Prevention, U.S.Clinical Laboratory ServicesEbolavirusEpidemicsFemaleGuineaHemorrhagic Fever, EbolaHumansInternational CooperationLiberiaMaleNational Institute of Allergy and Infectious Diseases (U.S.)SafetySierra LeoneUnited StatesdiagnosticsEbola virusepidemicmobile laboratoryWest Africa

Identifiers

PMID27333914
PMCPMC5050467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.