ArticlePloS one2016
Associations between Diabetes and Quality of Life among Breast Cancer Survivors.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Health-related quality of life in Asian patients with breast cancer: a systematic review.BMJ open · 2018Pooled it
- Diabetes mellitus and health-related quality of life in long-term survivors of breast, colorectal or prostate cancer: a population-based prospective study.British journal of cancer · 2026Article
- Sleep Disturbances in Type 1 Diabetes and Mitigating Cardiovascular Risk.The Journal of clinical endocrinology and metabolism · 2024Review
- The association of diabetes mellitus and routinely collected patient-reported outcomes in patients with cancer. A real-world cohort study.Cancer medicine · 2024Article
- Article
- Article
- Assessing the Quality of Life in Breast Cancer Women: A Cross Sectional Descriptive Study.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Temporal patterns of chronic disease incidence after breast cancer: a nationwide population-based cohort study.Scientific reports · 2022Article
- Differences in Health-Related Outcomes and Health Care Resource Utilization in Breast Cancer Survivors With and Without Type 2 Diabetes.Journal of patient-centered research and reviews · 2022Article
- Effect of chronic comorbidities on quality of life of gynecologic cancer patients in Puerto Rico.Revista panamericana de salud publica = Pan American journal of public health · 2022Article
- Metabolic comorbidities and medical institution utilization among breast cancer survivors: a national population-based study.The Korean journal of internal medicine · 2020Article
- Sleep-related disorders in patients with type 1 diabetes mellitus: current insights.Nature and science of sleep · 2020Review
- A simple screening score to predict diabetes in cancer patients: A Korean nationwide population-based cohort study.Medicine · 2019Article
- Impact of Diabetes on the Symptoms of Breast Cancer Survivors.Oncology nursing forum · 2019Article
- Quality of life of women with breast cancer undergoing treatment and follow-up at King Salman Armed Forces Hospital in Tabuk, Saudi Arabia.Breast cancer (Dove Medical Press) · 2019Article
- Cancer and comorbidity: The role of leptin in breast cancer and associated pathologies.World journal of clinical cases · 2018Review
- Glucose insult elicits hyperactivation of cancer stem cells through miR-424-cdc42-prdm14 signalling axis.British journal of cancer · 2017Article
- High-concentration glucose enhances invasion in invasive ductal breast carcinoma by promoting Glut1/MMP2/MMP9 axis expression.Oncology letters · 2017Article
- The predictors of poor quality of life in a sample of Saudi women with breast cancer.Breast cancer (Dove Medical Press) · 2017Article
- Understanding the Quality of Life Among Patients With Cancer in Saudi Arabia: Insights From a Cross-Sectional Study.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aimed to investigate the associations between diabetes and quality of life (QOL) among breast cancer survivors.
methodsA cross-sectional survey was conducted at 34 Cancer Recovery Clubs across China from May 2014 to January 2015. Quality of life was measured by the Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and the Quality of Life Questionnaire-Breast Cancer Module 23 (QLQ-BR23, simplified Chinese version). Information on social-demography, diagnosis and treatment of tumors, and diabetes mellitus were collected by self-reported questionnaires. Univariate analyses of covariance (ANCOVA) was performed to assess the difference in QOL between patients with or without diabetes mellitus, and multiple linear regression models were used to examine the associations after controlling for confounders.
resultsDiabetes, both of type 1 diabetes (T1DM) and type 2 diabetes (T2DM) significantly reduced QOL. This effect of diabetes on QOL is independent of tumor size, regional lymph node metastasis, distant metastasis and tumor stage index (TNM). After adjusting for different social-demography, diagnosis and treatment of the tumor, the tumor's stage and other chronic comorbidities, breast cancer survivors with diabetes got significantly lower scores in functional dimensions (including physical, role, emotional and social functionings measured by EORTC QLQ-C30; body image (BRBI) and future perspective (BRFU) measured by QLQ-BR23, as well as economic difficulties than those without diabetes (Padjusted<0.05). Diabetic patients also obtained higher scores in symptom dimensions, including fatigue, nausea and vomiting, pain, dyspnoea, insomnia, constipation and diarrhoea measured by EORTC QLQ-C30; side effects, breast symptoms and upset by hair loss measured by QLQ-BR23 (Padjusted<0.05). Compared to patients with T1DM, those with T2DM are likely to suffer more by loss of functioning.
conclusionsDiabetes was associated with the decreased QOL for breast cancer survivors.
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