Trial reportEBioMedicine2016
Human Recombinant Hyaluronidase Injections For Upper Limb Muscle Stiffness in Individuals With Cerebral Injury: A Case Series.
Trial report in EBioMedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multimodal Imaging Biomarkers for Investigating Fascia, Muscle and Vasculature in Myofascial Pain
The Efficacy of Fascial Manipulation Compared to Stretching in the Rehabilitation of Children With Cerebral Palsy
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Hyaluronidase Protocol in Management of Hyaluronic Acid Filler-Related Vascular Complications: A Systematic Review and Meta-Analysis.Aesthetic plastic surgery · 2026Pooled it
- Alterations in intramuscular connective tissue in hypertonic muscle: a scoping review.Frontiers in physiology · 2025Pooled it
- Characterization and clinical implications of ankle impedance during walking in chronic stroke.Scientific reports · 2021Trial
- Fascial Manipulation Compared to Stretching for Rehabilitation of Children With Cerebral Palsy: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2026Article
- Fascia as a Functional System in Health and Disease: From Fundamental Biology to Assessment and Targeted Interventions.International journal of molecular sciences · 2026Review
- Review
- Combination Hyaluronidase and Triamcinolone Acetonide Enzymatic Injections for Treatment of Ledderhose Disease: A Novel Technique and Case Series.Clinics and practice · 2026Article
- The myofascial rheostat: hyaluronan molecular weight dynamics and purinergic signalling as a physiological feedback system.Frontiers in physiology · 2026Review
- The Safety, Tolerability, and Pharmacokinetics of ALT-BB4 (A Novel Recombinant Hyaluronidase): A Randomized, Double-Blinded, Placebo-Controlled, Phase 1 Study in Healthy Volunteers.Dermatology and therapy · 2025Article
- Quantifying structural properties of forearm flexor muscles in individuals with hemiparetic cerebral palsy using diffusion tensor imaging.Physiological reports · 2025Article
- Muscle physiology and the science of tone agents.Pediatric research · 2025Review
- Excitation-inhibition imbalance in the motor control network: a key factor in post-stroke spasticity.Frontiers in human neuroscience · 2025Review
- Ultrasound Imaging Comparison of Crural Fascia Thickness and Muscle Stiffness in Stroke Patients with Spasticity.Diagnostics (Basel, Switzerland) · 2024Article
- Role of joint interactions in upper limb joint movements: a disability simulation study using wearable inertial sensors for 3D motion capture.Journal of neuroengineering and rehabilitation · 2024Article
- High-Level Extracellular Expression of Hyaluronate Lyase HylP in Bacillus subtilis for Hyaluronan Degradation.Applied biochemistry and biotechnology · 2024Article
- The effect of fascial manipulation therapy on lower limb spasticity and ankle clonus in stroke patients.European journal of translational myology · 2024Article
- Assessing muscle architecture with ultrasound: implications for spasticity.European journal of translational myology · 2024Article
- Short-Term Benefits from Manual Therapy as an Adjunct Treatment for Persistent Postural-Perceptual Dizziness Symptoms: A Preliminary Prospective Case Series.Journal of functional morphology and kinesiology · 2024Article
- Alignment, cross linking, and beyond: a collagen architect's guide to the skeletal muscle extracellular matrix.American journal of physiology. Cell physiology · 2023Review
- A pilot study on lengthening potentials and biomechanical effects of double and triple hemisection on tendon with slide lengthening.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.