ReviewCancers2016
Tomato as a Source of Carotenoids and Polyphenols Targeted to Cancer Prevention.
Review in Cancers, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
94 citing papers in PubMed, 2 syntheses or guidelines pooled it, 324 citations in OpenAlex.
- Potential Use of Tomato Peel, a Rich Source of Lycopene, for Cancer Treatment.Molecules (Basel, Switzerland) · 2024Pooled it
- Processed and raw tomato consumption and risk of prostate cancer: a systematic review and dose-response meta-analysis.Prostate cancer and prostatic diseases · 2018Pooled it
- Article
- From Genetic Diversity to Genetic Gain: Molecular Approaches and Breeding Strategies in Tomato with Insights from Lithuanian Germplasm.International journal of molecular sciences · 2026Review
- Morpho-phytochemical and molecular diversity in cherry tomato (Solanum lycopersicum var. cerasiforme) germplasm.Scientific reports · 2026Article
- Genetic architecture of the tomato fruit lipidome.PNAS nexus · 2026Article
- Improving tomato yield and production economics with Nano-NPK fertilization and salicylic acid chemigation.PloS one · 2026Article
- Carotenoid Biofortification in Field-Grown Tomato Fruits by Early Inoculation with Arbuscular Mycorrhizal Fungi.Journal of agricultural and food chemistry · 2025Article
- Association mapping of tomato fruit quality for weight, firmness, brix, and color using GWAS.BMC plant biology · 2025Article
- Metabolic Profiling and Functional Metabolite Distribution in Colored Tomatoes.Foods (Basel, Switzerland) · 2025Article
- In Vitro Insights into the Antifungal, Prebiotic, and Cytotoxic Potential of Tomato Plant Waste.Nutrients · 2025Article
- Profiling Neuroactive Compounds in Organic, Conventional, and Processed Tomatoes.Foods (Basel, Switzerland) · 2025Article
- Sustainable Fertilization with Ramial Chipped Wood Enhances Antioxidant Profiles in Tomato Varieties: An Untargeted Metabolomics Approach.Antioxidants (Basel, Switzerland) · 2025Article
- In Vivo Assessment of the Photoprotective Potential of Underutilized Carob Fractions by UsingPlants (Basel, Switzerland) · 2025Article
- Flavonoid-Based Combination Therapies and Nano-Formulations: An Emerging Frontier in Breast Cancer Treatment.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Polyphenol Content and Antioxidant Activity in Homemade and Commercial Soups: A Theoretical and Experimental Approach.Antioxidants (Basel, Switzerland) · 2025Article
- Evaluation of Phenolic Compounds and Antioxidant Activity in Three Black Cherry Tomato Varieties Grown Under Greenhouse Conditions.Plants (Basel, Switzerland) · 2025Article
- Obesity and Skin Carotenoid Score in Children from Center-Southern Italian Regions.Antioxidants (Basel, Switzerland) · 2025Article
- Effects of biochar, N-enriched biochar and urea on tomato seed germination, vegetative growth, and fruit traits.Journal of the science of food and agriculture · 2025Article
- Moderate salt stress aids in the enhancement of nutritional and flavor quality in tomato (Food chemistry: X · 2025Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A diet rich in vegetables has been associated with a reduced risk of many diseases related to aging and modern lifestyle. Over the past several decades, many researches have pointed out the direct relation between the intake of bioactive compounds present in tomato and a reduced risk of suffering different types of cancer. These bioactive constituents comprise phytochemicals such as carotenoids and polyphenols. The direct intake of these chemoprotective molecules seems to show higher efficiencies when they are ingested in its natural biological matrix than when they are ingested isolated or in dietary supplements. Consequently, there is a growing trend for improvement of the contents of these bioactive compounds in foods. The control of growing environment and processing conditions can ensure the maximum potential accumulation or moderate the loss of bioactive compounds, but the best results are obtained developing new varieties via plant breeding. The modification of single steps of metabolic pathways or their regulation via conventional breeding or genetic engineering has offered excellent results in crops such as tomato. In this review, we analyse the potential of tomato as source of the bioactive constituents with cancer-preventive properties and the result of modern breeding programs as a strategy to increase the levels of these compounds in the diet.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.