ArticleSensors (Basel, Switzerland)2016
Love Acoustic Wave-Based Devices and Molecularly-Imprinted Polymers as Versatile Sensors for Electronic Nose or Tongue for Cancer Monitoring.
Article in Sensors (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 32 citations in OpenAlex.
- Toward an understanding of microalgae EPS-based selectivity and binding mechanisms for trace metal ions using Love wave acoustic and voltammetric sensors in seawater.RSC advances · 2026Article
- Molecularly Imprinted Membranes for Selective Biomarker Recognition: Recent Advances and Emerging Strategies.Chem & bio engineering · 2025Review
- Advanced Love wave sensor based on algal polymers for the detection of mercury in French Guiana waters.Scientific reports · 2025Article
- Recent Advances in SAW Sensors for Detection of Cancer Biomarkers.Biosensors · 2025Review
- Trends and Applications of Surface and Bulk Acoustic Wave Devices: A Review.Micromachines · 2022Review
- Bulk and Surface Acoustic Wave Sensor Arrays for Multi-Analyte Detection: A Review.Sensors (Basel, Switzerland) · 2019Review
- Molecularly Imprinted Polymer-Based Microfluidic Systems for Point-of-Care Applications.Micromachines · 2019Review
- Study on Fabrication of ZnO Waveguide Layer for Love Wave Humidity Sensor Based on Magnetron Sputtering.Sensors (Basel, Switzerland) · 2018Article
- Enhanced Sensitivity of a Love Wave-Based Methane Gas Sensor Incorporating a Cryptophane-A Thin Film.Sensors (Basel, Switzerland) · 2018Article
- Love Wave Sensor for Prostate-Specific Membrane Antigen Detection Based on Hydrophilic Molecularly-Imprinted Polymer.Polymers · 2018Article
- MIP-Based Sensors: Promising New Tools for Cancer Biomarker Determination.Sensors (Basel, Switzerland) · 2017Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer is a leading cause of death worldwide and actual analytical techniques are restrictive in detecting it. Thus, there is still a challenge, as well as a need, for the development of quantitative non-invasive tools for the diagnosis of cancers and the follow-up care of patients. We introduce first the overall interest of electronic nose or tongue for such application of microsensors arrays with data processing in complex media, either gas (e.g., Volatile Organic Compounds or VOCs as biomarkers in breath) or liquid (e.g., modified nucleosides as urinary biomarkers). Then this is illustrated with a versatile acoustic wave transducer, functionalized with molecularly-imprinted polymers (MIP) synthesized for adenosine-5'-monophosphate (AMP) as a model for nucleosides. The device including the thin film coating is described, then static measurements with scanning electron microscopy (SEM) and electrical characterization after each step of the sensitive MIP process (deposit, removal of AMP template, capture of AMP target) demonstrate the thin film functionality. Dynamic measurements with a microfluidic setup and four targets are presented afterwards. They show a sensitivity of 5 Hz·ppm(-1) of the non-optimized microsensor for AMP detection, with a specificity of three times compared to PMPA, and almost nil sensitivity to 3'AMP and CMP, in accordance with previously published results on bulk MIP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.