Evidence map›Paper›PMID 27331112›Full record

ArticleData in brief2016

Proteomic dataset for altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells.

Razan Sheta, Florence Roux-Dalvai, Christina M Woo, Frédéric Fournier, Sylvie Bourassa, Carolyn R Bertozzi, Arnaud Droit, Dimcho Bachvarov

Abstract read
In one paragraph

Article in Data in brief, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. GALNT6 suppresses progression of colorectal cancer.American journal of cancer research · 2018
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Razan ShetaDepartment of Molecular Medicine, Laval University, Québec PQ, Canada; Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec PQ, Canada.
Florence Roux-DalvaiCentre de recherche du CHU de Québec, CHUL, Québec PQ, Canada.
Christina M WooDepartment of Chemistry, Stanford University, Stanford, CA, USA.
Frédéric FournierCentre de recherche du CHU de Québec, CHUL, Québec PQ, Canada.
Sylvie BourassaCentre de recherche du CHU de Québec, CHUL, Québec PQ, Canada.
Carolyn R BertozziDepartment of Chemistry, Stanford University, Stanford, CA, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
Arnaud DroitDepartment of Molecular Medicine, Laval University, Québec PQ, Canada; Centre de recherche du CHU de Québec, CHUL, Québec PQ, Canada.
Dimcho BachvarovDepartment of Molecular Medicine, Laval University, Québec PQ, Canada; Centre de recherche du CHU de Québec, L'Hôtel-Dieu de Québec, Québec PQ, Canada.

Funding

Investigating the Surface GlycoproteomeR01CA200423 · NCI · STANFORD UNIVERSITY · PI Carolyn Bertozzi · 2015 to 2026
$3.8M
NCI NIH HHS R01 CA200423
6 · The paper itself

Abstract

This article contains raw and processed data related to research published in "Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation" [1]. The data presented here was obtained with the application of a bioorthogonal chemical reporter strategy analyzing differential glycoprotein expression following the knock-down (KD) of the GALNT3 gene in the epithelial ovarian cancer (EOC) cell line A2780s. LC-MS/MS mass spectrometry analysis was then performed and the processed data related to the identified glycoproteins show that several hundred proteins are differentially expressed between control and GALNT3 KD A2780s cells. The obtained data also uncover numerous novel glycoproteins; some of which could represent new potential EOC biomarkers and/or therapeutic targets.

Indexed as

Ac4GalNAz labelingGALNT3GlycoproteomicsGlycosylationLabel free quantificationNetOGlyc and NetNGlyc prediction analysis

Identifiers

PMID27331112
PMCPMC4908283

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.