ArticleMolecular and clinical oncology2016
Detection of cancer embryo antigen and endothelin-1 in exhaled breath condensate: A novel approach to investigate non-small cell lung cancer.
Article in Molecular and clinical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Dynamic Changes in Exhaled Breath Glucose by Condensate Collection During Oral Glucose Tolerance Testing in Healthy Adults.Medical devices (Auckland, N.Z.) · 2026Article
- Role of nitric oxide, prostaglandins, thromboxanes and endothelins in lung cancer: An overview.World journal of clinical cases · 2025Review
- EDN1 facilitates cisplatin resistance of non-small cell lung cancer cells by regulating the TNF signaling pathway.World journal of surgical oncology · 2025Article
- The Role of Exhaled Breath Condensate in Chronic Inflammatory and Neoplastic Diseases of the Respiratory Tract.International journal of molecular sciences · 2024Review
- Sleeve gastrectomy ameliorates endothelial function and prevents lung cancer by normalizing endothelin-1 axis in obese and diabetic rats.World journal of gastroenterology · 2020Article
- Significance of vascular endothelium growth factor testing in exhaled breath condensate of patients with acute respiratory distress syndrome.Technology and health care : official journal of the European Society for Engineering and Medicine · 2020Article
- Clinical value of exhaled breath condensate let-7 in non-small cell lung cancer.International journal of clinical and experimental pathology · 2020Article
- Epidermal Growth Factor in Exhaled Breath Condensate as Diagnostic Method for Non-Small Cell Lung Cancer.Technology in cancer research & treatment · 2019Article
- The prognostic value of neutrophil to lymphocyte and platelet to lymphocyte ratios for patients with lung cancer.Oncology letters · 2017Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aimed to investigate the clinical significance of cancer embryo antigen (CEA) and endothelin-1 (ET-1) in the exhaled breath condensate (EBC) of patients with non-small cell lung cancer (NSCLC). EBC samples were collected from 143 patients with NSCLC and 119 healthy individuals by using an EBC collector. The CEA and ET-1 levels in the EBC and serum were detected. The levels of CEA and ET-1 in the serum and EBC of the NSCLC group were higher compared with those of the healthy group. The level of CEA in the EBC of the adenocarcinoma group was higher compared with that in the squamous cell carcinoma group. The levels of CEA and ET-1 in the serum and EBC in stages III and IV were higher compared with those in stages I and II. The levels of CEA and ET-1 in the EBC were positively correlated with those in the serum, and furthermore, they exhibited high specificity and sensitivity. Thus, these parameters may be used to diagnose lung cancer. The detection of CEA and ET-1 in EBC may help the process of diagnosing and monitoring the progression of NSCLC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.