Evidence map›Paper›PMID 27330702›Full record

ReviewJournal of lasers in medical sciences2016

Can Antimicrobial Photodynamic Therapy (aPDT) Enhance the Endodontic Treatment?

Nasim Chiniforush, Maryam Pourhajibagher, Sima Shahabi, Emad Kosarieh, Abbas Bahador

Registry-linked trialOpen access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of lasers in medical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07254260 (Photodynamic Therapy), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07254260 completednot on this mapstarted 2025, after this paper: background citation

Photodynamic Therapy (PDT) and Postendodontic Pain

TypeobservationalSponsorAtlas UniversityRan2025 to 2025Enrolled95ConditionsPulpitisArmsPhotodynamic Therapy
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.

  1. Pooled it
  2. Evaluation of antimicrobial photodynamic therapy with Butyl toluidine blue O for inactivation of Aggregatibacter actinomycetemcomitans biofilm.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
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  7. Reduction ofJournal of lasers in medical sciences · 2024
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  19. Iranian endodontic journal · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nasim ChiniforushLaser Research Center of Dentistry, Dental Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Maryam PourhajibagherDepartment of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Sima ShahabiDental biomaterials Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Emad KosariehLaser Research Center of Dentistry, Dental Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Abbas BahadorDepartment of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to achieve a long-lasting effect, one of the main goals in root canal treatment is to eliminate the endodontic bacteria. Conventional chemomechanical debridement is considered as the basic treatment in root canal therapy, but adjunctive techniques such as antimicrobial photodynamic therapy (aPDT) can also be helpful. The aim of this study was to evaluate reports in the scientific literature that used different photosensitizers (PSs) for bacterial reduction. The literature search was conducted using databases including PubMed, Scopus, and Google Scholar with the keywords "photodynamic therapy," "antimicrobial photodynamic therapy," or "photoactivated disinfection" and "endodontic," "Enterococcus faecalis," or "root canal treatment," from 2000 to 2015. By evaluating different studies, it was concluded that aPDT should be applied in combination with conventional mechanical debridement and irrigants. However, it is also important to note that the success rate is critically dependent on the type of the PS, output power of the laser used, irradiation time, pre-irradiation time, and type of tips used.

Indexed as

AntimicrobialEndodonticPhotodynamic therapy

Identifiers

PMID27330702
PMCPMC4909016
OpenAlexW2298938702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.