ArticleBiotechnology for biofuels2016
The sorghum SWEET gene family: stem sucrose accumulation as revealed through transcriptome profiling.
Article in Biotechnology for biofuels, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
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70 citing papers in PubMed.
- Molecular mechanisms and evolutionary adaptations of transporters for photosynthates and specialized metabolites in plants.Plant cell reports · 2026Review
- Soluble sugar component-based quality assessment and SWEET transport family identification uncovering soluble sugar accumulation mechanism inFrontiers in plant science · 2026Article
- QTL mapping and candidate genes prediction for plant height and brix content in sorghum [Sorghum bicolor (L.) Moench].TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Identification and Expression Pattern Analysis ofInternational journal of molecular sciences · 2025Article
- Genome-Wide Identification and Expression Profiling of Plasma Membrane-Localized SWEET Gene Family Associated with Sugar Transport During Yam Tuber Development.International journal of molecular sciences · 2025Article
- Unveiling shared genetic regulators of plant architectural and biomass yield traits in the Sorghum Association Panel.Journal of experimental botany · 2025Article
- Genome-Wide Identification of the SWEET Gene Family and Functional Analysis ofInternational journal of molecular sciences · 2025Article
- Characterization of theInternational journal of molecular sciences · 2025Article
- Unveiling the Genomic Symphony: Identification Cultivar-Specific Genes and Enhanced Insights on Sweet Sorghum Genomes Through Comprehensive superTranscriptomic Analysis.Journal of molecular evolution · 2024Article
- Genome wide identification of BjSWEET gene family and drought response analysis of BjSWEET12 and BjSWEET17 genes in Brassica juncea.BMC plant biology · 2024Article
- Genome-wide analysis of the SWEET gene family and its response to powdery mildew and leaf spot infection in the common oat (Avena sativa L.).BMC genomics · 2024Article
- Characterization and Transcriptomic Analysis of Sorghum EIN/EIL Family and Identification of Their Roles in Internode Maturation.Plants (Basel, Switzerland) · 2024Article
- Potential Roles of the GRF Transcription Factors in Sorghum Internodes during Post-Reproductive Stages.Plants (Basel, Switzerland) · 2024Article
- Genome-wide analysis of the SWEET gene family in Hemerocallis citrina and functional characterization of HcSWEET4a in response to salt stress.BMC plant biology · 2024Article
- Genome-Wide Bioinformatics Analysis ofPlants (Basel, Switzerland) · 2024Article
- Divergent Retention of Sucrose Metabolism Genes after Whole Genome Triplication in the Tomato (Plants (Basel, Switzerland) · 2023Article
- Harnessing the Genetic Basis of Sorghum Biomass-Related Traits to Facilitate Bioenergy Applications.International journal of molecular sciences · 2023Article
- An Insight ofInternational journal of molecular sciences · 2023Article
- Article
- Genome-wide identification, characterization and transcriptional profile of the SWEET gene family in Dendrobium officinale.BMC genomics · 2023Article
10 more citing papers are in PubMed but not listed here.
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Abstract
backgroundSWEET is a newly identified family of sugar transporters. Although SWEET transporters have been characterized by using Arabidopsis and rice, very little knowledge of sucrose accumulation in the stem region is available, as these model plants accumulate little sucrose in their stems. To elucidate the expression of key SWEET genes involved in sucrose accumulation of sorghum, we performed transcriptome profiling by RNA-seq, categorization using phylogenetic trees, analysis of chromosomal synteny, and comparison of amino acid sequences between SIL-05 (a sweet sorghum) and BTx623 (a grain sorghum).
resultsWe identified 23 SWEET genes in the sorghum genome. In the leaf, SbSWEET8-1 was highly expressed and was grouped in the same clade as AtSWEET11 and AtSWEET12 that play a role in the efflux of photosynthesized sucrose. The key genes in sucrose synthesis (SPS3) and that in another step of sugar transport (SbSUT1 and SbSUT2) were also highly expressed, suggesting that sucrose is newly synthesized and actively exported from the leaf. In the stem, SbSWEET4-3 was uniquely highly expressed. SbSWEET4-1, SbSWEET4-2, and SbSWEET4-3 were categorized into the same clade, but their tissue specificities were different, suggesting that SbSWEET4-3 is a sugar transporter with specific roles in the stem. We found a putative SWEET4-3 ortholog in the corresponding region of the maize chromosome, but not the rice chromosome, suggesting that SbSWEET4-3 was copied after the branching of sorghum and maize from rice. In the panicle from the heading through to 36 days afterward, SbSWEET2-1 and SbSWEET7-1 were expressed and grouped in the same clade as rice OsSWEET11/Xa13 that is essential for seed development. SbSWEET9-3 was highly expressed in the panicle only just after heading and was grouped into the same clade as AtSWEET8/RPG1 that is essential for pollen viability. Five of 23 SWEET genes had SNPs that caused nonsynonymous amino acid substitutions between SIL-05 and BTx623.
conclusionsWe determined the key SWEET genes for technological improvement of sorghum in the production of biofuels: SbSWEET8-1 for efflux of sucrose from the leaf; SbSWEET4-3 for unloading sucrose from the phloem in the stem; SbSWEET2-1 and SbSWEET7-1 for seed development; SbSWEET9-3 for pollen nutrition.
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