Evidence map›Paper›PMID 27330531›Full record

ArticleEXCLI journal2016

Sensitivity of clinical isolates of Candida to essential oils from Burseraceae family.

Miloš Nikolic, Marija Smiljkovic, Tatjana Markovic, Ana Cirica, Jasmina Glamoclija, Dejan Markovic, Marina Sokovic

Open access · greenAbstract read
In one paragraph

Article in EXCLI journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
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  6. Review of the Chemical Composition, Pharmacological Effects, Pharmacokinetics, and Quality Control ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Miloš NikolicInstitute for Biological Research "Siniša Stankovic", University of Belgrade, Bulevar Despota Stefana 142, 11000, Belgrade, Serbia.
Marija SmiljkovicInstitute for Biological Research "Siniša Stankovic", University of Belgrade, Bulevar Despota Stefana 142, 11000, Belgrade, Serbia.
Tatjana MarkovicInstitute for Medicinal Plant Research "Josif Pancic", Tadeuša Košcuška 2, 11000 Belgrade, Serbia.
Ana CiricaInstitute for Biological Research "Siniša Stankovic", University of Belgrade, Bulevar Despota Stefana 142, 11000, Belgrade, Serbia.
Jasmina GlamoclijaInstitute for Biological Research "Siniša Stankovic", University of Belgrade, Bulevar Despota Stefana 142, 11000, Belgrade, Serbia.
Dejan MarkovicFaculty of Dental Medicine, Department of Pediatric and Preventive Dentistry, University of Belgrade, dr Subotica 8, 11000 Belgrade, Serbia.
Marina SokovicInstitute for Biological Research "Siniša Stankovic", University of Belgrade, Bulevar Despota Stefana 142, 11000, Belgrade, Serbia.
Institute for Plant Protection and Environment · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the chemical composition and antifungal activity of four commercial essential oils from the Burseraceae family - two Boswellia carterii Flueck oils, Canarium luzonicum (Blume) A. Gray oil, and Commiphora myrrha (Nees) Engl oil, against most common Candida spp. recovered from the human oral cavity. The essential oil samples were analyzed by GC-FID and GC/MS. The analysis showed that major essential oils' components were α-pinene (23.04 % and 31.84 %), limonene (45.62 %) and curzerene (34.65 %), respectively. Minimum inhibitory (MIC) and minimum fungicidal (MFC) concentrations were determined using a microdilution standardized technique. All tested Candida spp. clinical isolates and ATCC strains showed susceptibility to tested essential oils in a dose dependent manner. The strongest antifungal activity was shown by essential oil of B. carterii, sample 2; the average MIC values ranged from 1.25 to 1.34 mg/ml, and MFC values ranged from 2.50 to 3.75 mg/ml, depending on the fungus. This study supports the possible use of essential oils from the Bursecaceae family in reduction and elimination of Candida spp. populations in patients with oral cavity fungal infections.

Indexed as

BurseraceaeCandida spp.essential oilsoral candidosissusceptibility

Identifiers

PMID27330531
PMCPMC4908663
OpenAlexW2466253456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.