Evidence map›Paper›PMID 27330502›Full record

ArticleGastroenterology & hepatology2016

Noninvasive Measures of Liver Fibrosis and Severity of Liver Disease.

Catherine Lucero, Robert S Brown

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Gastroenterology & hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Catherine LuceroDr Lucero is an assistant professor of medicine in the Center for Liver Disease and Transplantation at Weill Cornell Medical Center in New York, New York. Dr Brown is the vice chair of Transitions of Care and the interim chief of the Division of Gastroenterology and Hepatology at Weill Cornell Medical Center.
Robert S BrownDr Lucero is an assistant professor of medicine in the Center for Liver Disease and Transplantation at Weill Cornell Medical Center in New York, New York. Dr Brown is the vice chair of Transitions of Care and the interim chief of the Division of Gastroenterology and Hepatology at Weill Cornell Medical Center.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Determining the degree of fibrosis is an important step in the assessment of disease severity in patients with chronic liver disease. Liver biopsy has been the gold standard for estimating the extent of inflammation and fibrosis, although the procedure has limitations such as sampling error and variability. Noninvasive testing has been shown to be equally predictive in ruling out fibrosis or ruling in advanced fibrosis. Serum biomarkers and imaging-based tests have more limited predictive ability when classifying intermediate stages, but these tools can help identify which patients should receive antiviral treatment sooner and require ongoing cancer surveillance without the need for biopsy. Using a combination of serum markers and imaging tests may also be helpful in providing functional assessment of portal hypertension in patients with chronic liver disease.

Indexed as

diagnostic testFibrosisimagingliver stiffnessnoninvasiveprognosis

Identifiers

PMID27330502
PMCPMC4865784

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.