Evidence map›Paper›PMID 27330458›Full record

ArticleDigital journal of ophthalmology : DJO2015

Retinal tears and rhegmatogenous retinal detachment after intravitreal injections: its prevalence and case reports.

Revan Yildirim Karabag, Melih Parlak, Gölgem Cetin, Aylin Yaman, A Osman Saatci

Abstract read
In one paragraph

Article in Digital journal of ophthalmology : DJO, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Pharmacokinetic model for drug delivery by Ozurdex.Drug delivery and translational research · 2026
    Article
  3. Systemic and ocular complications related to intravitreal administration of anti-VEGF agents.Medical hypothesis, discovery & innovation ophthalmology journal · 2026
    Review
  4. Intravitreal Dexamethasone Implant in Vitreoretinal Surgery: An Overview of the Literature.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
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  11. Ophthalmic delivery of hydrophilic drugs through drug-loaded oleogels.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2021
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Extended release of dexamethasone from oleogel based rods.Journal of colloid and interface science · 2019
    Article
  17. Article
  18. Article
  19. Light in diagnosis, therapy and surgery.Nature biomedical engineering · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Revan Yildirim KarabagDepartment of Ophthalmology, Dokuz Eylul University Medical School, Izmir, Turkey;
Melih ParlakDepartment of Ophthalmology, Klinikum Konstanz, Konstanz, Germany.
Gölgem CetinDepartment of Ophthalmology, Dokuz Eylul University Medical School, Izmir, Turkey;
Aylin YamanDepartment of Ophthalmology, Dokuz Eylul University Medical School, Izmir, Turkey;
A Osman SaatciDepartment of Ophthalmology, Dokuz Eylul University Medical School, Izmir, Turkey;

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report the prevalence of postoperative retinal tear or rhegmatogenous retinal detachment secondary to intravitreal injections.

methodsSurgical and medical records of patients who received intravitreal injections at the practice of a single retina specialist from January 2004 to May 2013 and who were followed for at least 6 months were investigated retrospectively.

resultsDuring the study period, a total of 3,907 intravitreal injections were performed in 1,049 eyes of 784 patients (416 males [47%]). The mean number of injections per eye was 3.72 ± 3.43 (range, 1-22). The mean age of the participants was 67.03 ± 13.56 (range, 5-94 years). The mean follow-up time was 31.98 ± 22.86 months (range, 6-144 months). Retinal break or rhegmatogenous retinal detachment occurred in 3 injections of 3 eyes, yielding an overall prevalence of 0.077% per injection and 0.29% per eye.

conclusionsRetinal tear and rhegmatogenous detachment are rare complications of intravitreal injection. Precautions should be taken especially in patients having predisposing conditions, such as high myopia, or any other vitreoretinal disorders.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolEye DiseasesFemaleHumansIntravitreal InjectionsMaleMiddle AgedOphthalmic SolutionsPostoperative ComplicationsRetinal DetachmentRetinal PerforationsOphthalmic Solutions

Identifiers

PMID27330458
PMCPMC4902634

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.