Evidence map›Paper›PMID 27330452›Full record

ArticleEpilepsy currents

2014 Epilepsy Benchmarks Area III: Improve Treatment Options for Controlling Seizures and Epilepsy-Related Conditions Without Side Effects.

Dennis Dlugos, Greg Worrell, Kathryn Davis, William Stacey, Jerzy Szaflarski, Andres Kanner, Sridhar Sunderam, Mike Rogawski, Patrice Jackson-Ayotunde, Tobias Loddenkemper and 4 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epilepsy currents. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04649008 (Optimized Intracranial EEG Targeting in Focal Epilepsy Based Upon Neuroimaging Connectomics), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04649008 early_phase1recruitingnot on this map

Optimized Intracranial EEG Targeting in Focal Epilepsy Based Upon Neuroimaging Connectomics

TypeinterventionalSponsorUniversity of PennsylvaniaRan2021 to 2027Enrolled290ConditionsEpilepsy, Epilepsy Intractable, Epilepsy, Temporal LobeArms3T Magnetic Resonance Imaging, Intracranial electroencephalography recordings, 7T Magnetic Resonance Imaging
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Dennis DlugosProfessor of Neurology and Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Greg WorrellAssociate Professor of Neurology, Mayo Systems Electrophysiology Laboratory, Departments of Neurology and Biomedical Engineering, Mayo Clinic, Rochester, MN.
Kathryn DavisAssistant Professor, Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
William StaceyAssistant Professor of Neurology, Department of Neurology, Department of Biomedical Engineering, University of Michigan.
Jerzy SzaflarskiProfessor, Department of Neurology, University of Alabama at Birmingham Department of Neurology and UAB Epilepsy Center, Birmingham, AL.
Andres KannerProfressor of Clinical Neurology, Department of Neurology, University of Miami, Miller School of Medicine, Miami, FL.
Sridhar SunderamAssistant Professor, Department of Biomedical Engineering, University of Kentucky, Lexington, KY.
Mike RogawskiProfessor, Center for Neurotherapeutics Discovery and Development and Department of Neurology, UC Davis School of Medicine, Sacramento, CA.
Patrice Jackson-AyotundeAssociate Professor, Department of Pharmaceutical Sciences, University of Maryland Eastern Shore, Princess Anne, MD.
Tobias LoddenkemperAssociate Professor, Division of Epilepsy and Clinical Neurophysiology, Department of Neurology, Boston Children's Hospital & Harvard Medical School, Boston, MA.
Beate DiehlClinical Neurophysiologist and Neurologist, Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK.
Brandy FuremanProgram Director, Channels Synapses and Circuits Cluster, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Ray DingledineProfessor and Chair, Department of Pharmacology, Emory University, Atlanta, GA.
Epilepsy Benchmark Stewards

Funding

Inflammatory control of blood-brain barrier integrity and epileptogenesis after seizuresR01NS097776 · NINDS · EMORY UNIVERSITY · PI DINGLEDINE, RAYMOND J · 2016 to 2020
$2.2M
NINDS NIH HHS R01 NS097776
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID27330452
PMCPMC4913858

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.