ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
Review of photon and proton radiotherapy for skull base tumours.
Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05861245 (Phase II Clinical Trial of Low-intervention Using Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base), which is not on this map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Phase II Clinical Trial of Low-intervention Using Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base
Who cites it
26 citing papers in PubMed, 46 citations in OpenAlex.
- Proton therapy for skull-base chondrosarcoma, a single-institution outcomes study.Journal of neuro-oncology · 2019Trial
- Outcomes of adjuvant radiation treatment following subtotal resection of world health organization grade II meningiomas.Journal of neuro-oncology · 2025Article
- Surgical management of skull base chordomas and chondrosarcomas: insights from a national cohort study.BMJ oncology · 2024Article
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- Radiation Therapy for Chordomas and Chondrosarcomas of the Skull Base: Evaluation of the Effectiveness of Treatment Methods (Review).Sovremennye tekhnologii v meditsine · 2023Review
- The contemporary management of cancers of the sinonasal tract in adults.CA: a cancer journal for clinicians · 2023Review
- Proton therapy with a fixed beamline for skull-base chordomas and chondrosarcomas: outcomes and toxicity.Radiation oncology (London, England) · 2021Article
- Therapeutic Efficacy of Variable Biological Effectiveness of Proton Therapy in U-CH2 and MUG-Chor1 Human Chordoma Cell Death.Cancers · 2021Article
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- Article
- Review
- A Review of Particle Therapy for Skull Base Tumors: Modern Considerations and Future Directions.International journal of particle therapy · 2021Article
- Proton Therapy in Head and Neck Cancer Treatment: State of the Problem and Development Prospects (Review).Sovremennye tekhnologii v meditsine · 2021Review
- Multivariate Analysis and Validation of the Prognostic Factors for Skull Base Chordoma.Frontiers in surgery · 2021Article
- Pituitary Dysfunction after Radiation for Anterior Skull Base Malignancies: Incidence and Screening.Journal of neurological surgery. Part B, Skull base · 2020Article
- The impact of proton LET/RBE modeling and robustness analysis on base-of-skull and pediatric craniopharyngioma proton plans relative to VMAT.Acta oncologica (Stockholm, Sweden) · 2019Article
- The preliminary results of proton and carbon ion therapy for chordoma and chondrosarcoma of the skull base and cervical spine.Radiation oncology (London, England) · 2019Article
- Surgery of the lateral skull base: a 50-year endeavour.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2019Review
- What Is the Effect of High-dose Radiation on Bone in Patients With Sacral Chordoma? A CT Study.Clinical orthopaedics and related research · 2018Article
- Does Proton Therapy Have a Future in CNS Tumors?Current treatment options in neurology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An extremely large variety of benign and malignant tumours occur at skull base; these tumour lesions are in the proximity to structures deputed to relevant physiologic functions, limiting extensive surgical approaches to this body district. Most recent progresses of surgery and radiotherapy have allowed to improve local control with acceptable rates of side effects. Various photon radiotherapy techniques are employed, including 3-dimensional conformal radiotherapy, intensity modulated radiotherapy (IMRT), stereotactic radiotherapy (SRT) and brachytherapy that is manly limited to the treatment of primary or recurrent nasopharyngeal carcinoma. Proton beam radiotherapy is also extensively used thanks to its physical characteristics. Our review, focusing in particular on meningioma, chordoma, and chondrosarcoma, suggests that proton therapy plays a major role in the treatment of malignant tumours whereas photon therapy still plays a relevant role in the treatment of benign tumour lesions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.