ReviewSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2016
Pain and anxiety management for pediatric dental procedures using various combinations of sedative drugs: A review.
Review in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03388957 (Evaluating of Oral Propranolol Effect on Managing Anxiety of Dental Extractions in Children), which is not on this map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating of Oral Propranolol Effect on Managing Anxiety of Dental Extractions in Children: A Randomized Controlled Clinical Trial
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Efficacy and Safety of Nitrous Oxide (NMedicina (Kaunas, Lithuania) · 2025Pooled it
- Sedative and adverse effect comparison between oral midazolam and nitrous oxide inhalation in tooth extraction: a meta-analysis.BMC oral health · 2023Pooled it
- Immediate postoperative anesthesia with either lidocaine or bupivacaine: A short-term clinical response.Journal of periodontology · 2025Trial
- Oral midazolam vs. intranasal dexmedetomidine plus oral midazolam for sedation of pediatric outpatients: a double-blinded randomized controlled trial.BMC anesthesiology · 2023Trial
- Comparison of paracetamol, ibuprofen, and diclofenac potassium for pain relief following dental extractions and deep cavity preparations.Saudi medical journal · 2017Trial
- Evaluation of dental treatments under nitrous oxide-oxygen inhalation sedation in pediatric patients with dental anxiety: a 10-Year retrospective study.BMC oral health · 2025Article
- Ultra-Low Frequency TENS as an Adjunctive Therapy for Pain Management in Non-Surgical Periodontal Treatment: A Pilot Study.Dentistry journal · 2025Article
- A Comparative Evaluation of Midazolam, Ketamine and Their Combination as Sedative Agents in Pediatric Dentistry: A Systematic Review and Meta-analysis.Frontiers in dentistry · 2025Review
- Exploring the Levels of Stress, Anxiety, Depression, Resilience, Hope, and Spiritual Well-Being Among Greek Dentistry and Nursing Students in Response to Academic Responsibilities Two Years After the COVID-19 Pandemic.Healthcare (Basel, Switzerland) · 2024Article
- The Effect of General Anesthesia on the Outcome of Root Canal Treatment in Pediatric Patients-A Retrospective Cohort Study.Children (Basel, Switzerland) · 2023Article
- Behaviour of 3-11-year-old children during dental treatment requiring multiple visits: a retrospective study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2022Article
- Comparative Analysis of Different Local Anesthetic Solutions Available in Market: An In Vitro and Clinical Study.European journal of dentistry · 2021Article
- Parental acceptance of advanced behaviour management techniques in paediatric dentistry in families with different cultural background.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2021Article
- Assessment of Nitrous Oxide Inhalation Sedation Module in Kuwait: A Survey on Undergraduate Dental Training Curriculum.Advances in medical education and practice · 2021Article
- Carers' and paediatric dentists' perceptions of children's pain during restorative treatment.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2020Article
- Parental acceptance of advanced behaviour management techniques in normal treatment and in emergency situations used in paediatric dentistry.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2019Article
- Use of sedative drugs at reducing the side effects of voiding cystourethrography in children.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Review
- Anesthetic approach to Niemann-Pick Type C patient for dental treatment.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Article
- Gene Therapy: A Paradigm Shift in Dentistry.Genes · 2016Review
- A randomized control trial comparing the visual and verbal communication methods for reducing fear and anxiety during tooth extraction.The Saudi dental journal · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For fearful and uncooperative children behavioral management techniques are used. In order to control the pain and anxiety in pedodontic patients, pharmacologic sedation, anesthesia and analgesia are commonly used. Midazolam is commonly used as an oral sedation agent in children; it has several features such as safety of use, quick onset and certain degree of amnesia that makes it a desirable sedation agent in children. This review paper discusses various aspects of oral midazolam, ketamine and their combinations in conscious sedation including, advantages of oral route of sedation, pharmacokinetics, range of oral doses, and antagonists for clinical dental treatment procedures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.