ReviewSubstance abuse and rehabilitation2016
Identifying and assessing the risk of opioid abuse in patients with cancer: an integrative review.
Review in Substance abuse and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.
- Unveiling Prescribing Patterns: A Systematic Review of Chronic Opioid Prescriptions After Head and Neck Cancer Surgeries.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Pooled it
- Article
- Comparative Effectiveness of Opioids and Opioid Substitutes on Pain and Health Related Quality of Life Among Cancer Survivors.Cancer medicine · 2025Article
- Women With Gynecologic Cancers: Screening for Substance Use Disorders Is Key.Journal of the advanced practitioner in oncology · 2025Article
- Opioid Use in Cancer Pain Management: Navigating the Line Between Relief and Addiction.International journal of molecular sciences · 2025Review
- Palliative care for people with substance use disorders: a qualitative study of the experiences of rural primary care providers.BMC palliative care · 2025Article
- Medication misuse and illicit substance use among palliative care patients in German palliative care units- an evaluation from the perspective of palliative care providers.Addiction science & clinical practice · 2025Article
- Abuse-deterrent wearable device with potential for extended delivery of opioid drugs.Biomedical engineering letters · 2025Article
- The Legal Landscape for Opioid Treatment Agreements.The Milbank quarterly · 2024Article
- Creating a Palliative Care Clinic for Patients with Cancer Pain and Substance Use Disorder.Journal of pain and symptom management · 2024Article
- Neuropsychiatric Effects Associated with Opioid-Based Management for Palliative Care Patients.Current pain and headache reports · 2024Review
- Article
- Prevalence of abnormal urine drug tests during COVID-19 pandemic in the cancer patient population: retrospective study.Pain management · 2024Article
- Opioid use in cancer patients compared with noncancer pain patients in a veteran population.JNCI cancer spectrum · 2024Article
- Effect of Tissue Expanders Filled With Saline Versus Air on Longitudinal Breast Reconstruction Outcomes.Eplasty · 2024Article
- Assessing risk for nonmedical opioid use among patients with cancer: Stability of the CAGE-AID questionnaire across clinical care settings.Palliative & supportive care · 2023Article
- The Stigma Surrounding Opioid Use as a Barrier to Cancer-Pain Management: An Overview of Experiences with Fear, Shame, and Poorly Controlled Pain in the Context of Advanced Cancer.Current oncology (Toronto, Ont.) · 2023Review
- "I Refused to Get Addicted to Opioids": Exploring Attitudes About Opioid Use Disorder in Patients With Advanced Cancer Pain and Their Support People.The journal of pain · 2023Article
- Nonmedical opioid use at the end of life: A tale of addiction and a last wish.Palliative & supportive care · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe misuse and abuse of opioid medications in many developed nations is a health crisis, leading to increased health-system utilization, emergency department visits, and overdose deaths. There are also increasing concerns about opioid abuse and diversion in patients with cancer, even at the end of life.
aimsTo evaluate the current literature on opioid misuse and abuse, and more specifically the identification and assessment of opioid-abuse risk in patients with cancer. Our secondary aim is to offer the most current evidence of best clinical practice and suggest future directions for research. MATERIALS AND
methodsOur integrative review included a literature search using the key terms "identification and assessment of opioid abuse in cancer", "advanced cancer and opioid abuse", "hospice and opioid abuse", and "palliative care and opioid abuse". PubMed, PsycInfo, and Embase were supplemented by a manual search.
resultsWe found 691 articles and eliminated 657, because they were predominantly non cancer populations or specifically excluded cancer patients. A total of 34 articles met our criteria, including case studies, case series, retrospective observational studies, and narrative reviews. The studies were categorized into screening questionnaires for opioid abuse or alcohol, urine drug screens to identify opioid misuse or abuse, prescription drug-monitoring programs, and the use of universal precautions.
conclusionScreening questionnaires and urine drug screens indicated at least one in five patients with cancer may be at risk of opioid-use disorder. Several studies demonstrated associations between high-risk patients and clinical outcomes, such as aberrant behavior, prolonged opioid use, higher morphine-equivalent daily dose, greater health care utilization, and symptom burden.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.