ArticleJP journal of biostatistics2015
DETECTING CONFORMATIONAL DIFFERENCES BETWEEN RNA 3D STRUCTURES.
Article in JP journal of biostatistics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- SupeRNAlign: a new tool for flexible superposition of homologous RNA structures and inference of accurate structure-based sequence alignments.Nucleic acids research · 2017Article
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Authors and funding
2 authors.
Funding
Abstract
A method is described for detecting local conformational differences between two 3D structures of the same RNA molecule. These could be distinct 3D structures of the same molecule from the same organism, or homologous molecules from different organisms. In this approach, we detect the variability that exists among the relative translation and rotation operations that are needed to superimpose local neighborhoods after an initial rigid-body global superposition. Each translation and rotation is represented by a three dimensional vector. Thus, we investigate the variability within sets of multivariate data. We demonstrate that the method is able to identify both small- and large-scale conformational changes. Matlab/Octave programs to read RNA 3D structure files and compare structures have been developed and are freely accessible at: https://github.com/BGSU-RNA/ConformationalChange.
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