Evidence map›Paper›PMID 27330127›Full record

ArticleDiabetes care2016

Relative Contributions of Socioeconomic, Local Environmental, Psychosocial, Lifestyle/Behavioral, Biophysiological, and Ancestral Factors to Racial/Ethnic Disparities in Type 2 Diabetes.

Rebecca S Piccolo, S V Subramanian, Neil Pearce, Jose C Florez, John B McKinlay

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 67 citations in OpenAlex.

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  8. Factors Associated with Progression to Type 2 Diabetes among Women with Gestational Diabetes.Journal of urban health : bulletin of the New York Academy of Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Rebecca S PiccoloLondon School of Hygiene and Tropical Medicine, London, U.K. rebecca.piccolo@lshtm.ac.uk.
S V SubramanianHarvard T.H. Chan School of Public Health, Harvard University, Boston, MA.
Neil PearceLondon School of Hygiene and Tropical Medicine, London, U.K.
Jose C FlorezDiabetes Unit, Massachusetts General Hospital, and Harvard Medical School, Boston, MA.
John B McKinlayDepartment of Epidemiology, New England Research Institutes, Watertown, MA.
London School of Hygiene & Tropical Medicine · GBHarvard University · USMassachusetts General Hospital · USNew England Research Institutes · US

Funding

Trajectories of Urologic Disease: Follow-up of BACHU01DK056842 · NIDDK · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MCKINLAY, JOHN B · 2001 to 2011
$15.7M
Upstream Contributors to Downstream Disparities in Type 2 Diabetes - A Multi-LeveR01DK080786 · NIDDK · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MCKINLAY, JOHN B · 2009 to 2013
$3.3M
Trajectories of Urologic Disease: Follow-up of BACHR01DK056842 · NIDDK · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MCKINLAY, JOHN B · 2007 to 2007
$1.2M
NIDDK NIH HHS R01 DK056842NIDDK NIH HHS R01 DK080786NIDDK NIH HHS U01 DK056842
6 · The paper itself

Abstract

objectiveRacial/ethnic minorities in the U.S. have a higher prevalence of type 2 diabetes mellitus (T2DM) than white adults. While many independent risk factors for T2DM have been identified, these determinants are often viewed in isolation without considering the joint contributions of competing risk factors. The objective of this study was to assess the relative contributions of six domains of influence to racial/ethnic disparities in T2DM. RESEARCH DESIGN AND

methodsCross-sectional analyses were conducted using the Boston Area Community Health III Survey (2010-2012), the third wave of a population-based sample of men and women from three racial/ethnic groups (black, Hispanic, white) living in Boston, Massachusetts (N = 2,764). Prevalent diabetes was defined by self-report of T2DM, fasting glucose >125 mg/dL, or HbA1c ≥6.5%. Structural equation models were constructed to evaluate the direct effects of each conceptual domain of influence on T2DM prevalence, as well as their indirect effects on the race/ethnicity-T2DM relationship. All direct and indirect pathways were included.

resultsThe final model indicated that 38.9% and 21.8% of the total effect of black race and Hispanic ethnicity, respectively, on T2DM prevalence was mediated by the socioeconomic, environmental, psychosocial, and lifestyle/behavioral risk scores. The largest mediating influence was the socioeconomic risk score, which explained 21.8% and 26.2% of the total effect of black race and Hispanic ethnicity, respectively.

conclusionsOur study found that socioeconomic factors had the greatest impact on explaining the excess prevalence of T2DM among racial/ethnic minorities.

Indexed as

AdultAgedBostonCross-Sectional StudiesDiabetes Mellitus, Type 2EnvironmentEthnicityFemaleHealth BehaviorHealth SurveysHumansLife StyleMaleMiddle AgedPrevalenceResidence Characteristics

Identifiers

PMID27330127
PMCPMC4915558
OpenAlexW2460039851

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.