ArticleJournal of medical entomology2016
Critical Evaluation of the Linkage Between Tick-Based Risk Measures and the Occurrence of Lyme Disease Cases.
Article in Journal of medical entomology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it, 133 citations in OpenAlex.
- Systematic review and meta-analysis of tick-borne disease risk factors in residential yards, neighborhoods, and beyond.BMC infectious diseases · 2019Pooled it
- The ecology of Lyme disease: Long-term data, surprises, and a synthesis.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Assessing the Effectiveness of Crowdsourced Data to Detect Established Tick Populations in Quebec, Canada: Retrospective Ecological Study.JMIR public health and surveillance · 2026Article
- Bayesian Multivariate Modelling of Lone Star (International journal of environmental research and public health · 2026Article
- A double-blinded, placebo-controlled field trial of an OspA-based oral reservoir targeted vaccine against Borrelia burgdorferi.NPJ vaccines · 2026Article
- Why are the ticks winning, and what can we do about it?Ticks and tick-borne diseases · 2026Review
- A double-blinded, placebo-controlled field trial of an OspA-based oral reservoir targeted vaccine againstbioRxiv : the preprint server for biology · 2026Article
- Spatial modeling of Borrelia genospecies in human-biting ticks from the French citizen science programme CiTIQUE.Scientific reports · 2026Article
- Guillain-Barré Polyradiculoneuritis Developed in the Context of Lyme Neuroborreliosis in a 13-Year-Old Girl: A Case Report.Children (Basel, Switzerland) · 2026Article
- A Lyme Neuroborreliosis Case Presenting With Ophthalmoplegia, Dysarthria, and Spastic Quadriparesis.Cureus · 2026Article
- Spatial pattern assessment of Aedes mosquito bite risk in a subtropical metropolitan area: A case study in Shenzhen.PLoS neglected tropical diseases · 2025Article
- Risk Factors for Lyme Disease in the General Population-A Survey of Adults and Caregivers in 28 States.Open forum infectious diseases · 2025Article
- Modelling tick abundance and environmental suitability in meso-Mediterranean landscapes for the prevention of tick-borne diseases.PLoS neglected tropical diseases · 2025Article
- Environmental correlates and fine-scale distribution of Amblyomma americanum, Ehrlichia spp., and Rickettsia amblyommatis at a single site in south-central Virginia.Parasites & vectors · 2025Article
- A scoping review of applied tick control research in North America: funding, implementation, and advancement.Journal of medical entomology · 2025Article
- Prevalence and Genetic Diversity of Deer Tick Virus (Powassan Virus, Lineage II) in Ixodes scapularis Ticks in Five Habitats at a Nature Reserve in Southern Maine, United States.The American journal of tropical medicine and hygiene · 2024Article
- The Spread of Lone Star Ticks (Insects · 2024Article
- Prevalence of Lyme Disease and Relapsing FeverPathogens (Basel, Switzerland) · 2024Review
- Adapting vector surveillance using Bayesian experimental design: An application to an ongoing tick monitoring program in the southeastern United States.Ticks and tick-borne diseases · 2024Article
- Comparative Analysis of Bisexual and Parthenogenetic Populations in Haemaphysalis Longicornis.Microorganisms · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The nymphal stage of the blacklegged tick, Ixodes scapularis Say, is considered the primary vector to humans in the eastern United States of the Lyme disease spirochete Borrelia burgdorferi sensu stricto. The abundance of infected host-seeking nymphs is commonly used to estimate the fundamental risk of human exposure to B. burgdorferi, for the purpose of environmental risk assessment and as an outcome measure when evaluating environmentally based tick or pathogen control methods. However, as this tick-based risk measure does not consider the likelihoods of either human encounters with infected ticks or tick bites resulting in pathogen transmission, its linkage to the occurrence of Lyme disease cases is worth evaluating. In this Forum article, we describe different tick-based risk measures, discuss their strengths and weaknesses, and review the evidence for their capacity to predict the occurrence of Lyme disease cases. We conclude that: 1) the linkage between abundance of host-seeking B. burgdorferi-infected nymphs and Lyme disease occurrence is strong at community or county scales but weak at the fine spatial scale of residential properties where most human exposures to infected nymphs occur in Northeast, 2) the combined use of risk measures based on infected nymphs collected from the environment and ticks collected from humans is preferable to either one of these risk measures used singly when assessing the efficacy of environmentally based tick or pathogen control methods aiming to reduce the risk of human exposure to B. burgdorferi, 3) there is a need for improved risk assessment methodology for residential properties that accounts for both the abundance of infected nymphs and the likelihood of human-tick contact, and 4) we need to better understand how specific human activities conducted in defined residential microhabitats relate to risk for nymphal exposures and bites.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.