ArticleThe Journal of international medical research2016
Relationship between platelet parameters and hepatic pathology in patients with chronic hepatitis B infection - a retrospective cohort study of 677 patients.
Article in The Journal of international medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 23 citations in OpenAlex.
- The interferon-inducible MxB large GTPase attenuates hepatitis B virus replication by activating the RIG-I innate immunity signaling pathway.Scientific reports · 2025Article
- microRNAs and Other Serological Markers of Liver Fibrosis in Patients with Alcohol-Related Liver Cirrhosis.Biomedicines · 2024Article
- Direct Reciprocal Interaction Between Platelet Count and HBeAg Status in HBsAg-positive Pregnant Women.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2024Article
- Assessment of the performance of haematological and non-invasive fibrotic indices for the monitoring of chronic HBV infection: a pilot study in a Ghanaian population.BMC research notes · 2023Article
- Discontinuing Hepatitis Activity Reduced Hepatocellular Carcinoma Recurrence after Primary Curative Therapy.Journal of personalized medicine · 2023Article
- Platelet count is closely associated with the severity of liver injury in patients with chronic hepatitis B virus infection: A cross-sectional study.Experimental and therapeutic medicine · 2020Article
- The Utility of Platelet Indices in Predicting Multiorgan Dysfunction in Scrub Typhus.Interdisciplinary perspectives on infectious diseases · 2020Article
- Platelet distribution width as a novel indicator of disease activity in systemic lupus erythematosus.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018Article
- Noninvasive scoring system for significant inflammation related to chronic hepatitis B.Scientific reports · 2017Article
- Utility of platelet indices in alcoholic hepatitis: a retrospective study.Porto biomedical journalArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveA retrospective study to determine the relationships between platelet parameters and inflammation and fibrosis of the liver in patients with chronic hepatitis B virus infection (CHB).
methodsPatients with liver biopsy-confirmed CHB were included in the study. Liver fibrosis and inflammation were assessed by histopathology of biopsied liver tissue. Platelet count (PLT), platelet distribution width (PDW) and mean platelet volume (MPV) were determined as part of routine blood tests. The relationship between inflammation and fibrosis and platelet parameters were analysed by multiple linear regression.
resultsThe study included 677 patients. PLT and PDW accounted for 20.5% of liver inflammation. PLT and PDW accounted for 18.4% of liver fibrosis.
conclusionPlatelet parameters can provide valuable information for the assessment of hepatic inflammation and fibrosis.
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