Evidence map›Paper›PMID 27329349›Full record

ArticleScientific reports2016

Identification of a Novel Enterovirus Species in Rhesus Macaque in China.

Yuan-Yun Ao, Jie-Mei Yu, Cui-Yuan Zhang, Yun-Yun Xin, Li-Li Li, Zhao-Jun Duan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Virome diversity analysis reveals novel enteroviruses and a human picobirnavirus in stool samples from African green monkeys with diarrhea.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yuan-Yun AoNational Institute for Viral Disease Control and Prevention, China CDC, Beijing 100052, China.
Jie-Mei YuNational Institute for Viral Disease Control and Prevention, China CDC, Beijing 100052, China.
Cui-Yuan ZhangNational Institute for Viral Disease Control and Prevention, China CDC, Beijing 100052, China.
Yun-Yun XinThe First affiliated Hospital of Hunan Normal University, Changsha 410000, Hunan, China.
Li-Li LiNational Institute for Viral Disease Control and Prevention, China CDC, Beijing 100052, China.
Zhao-Jun DuanNational Institute for Viral Disease Control and Prevention, China CDC, Beijing 100052, China.
Chinese Center For Disease Control and Prevention · CNNational Institute for Viral Disease Control and Prevention · CNHunan Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies of Enterovirus (EV) in nonhuman primates (NHPs), which could act as a source of future emerging human viral diseases, have boosted interest in the search for novel EVs. Here, a highly divergent strain of EV, tentatively named SEV-gx, was identified by viral metagenomic analysis from stool samples of rhesus macaques in China. In total, 27 of 280 (9.6%) faecal samples from rhesus macaques were positive for SEV-gx. Its complete genomic sequence is 7,367 nucleotide (nt). Genomic analyses showed that it has a standard genomic organisation for EVs, being more closely related to EV-J strains (approximately 54.0%, 43.0-44.1%, 52.3-55.2%, 61.1-62.7% and 64.0% amino acids identity in polyprotein, P1, P2 and P3 and combined 2C/3CD regions, respectively). It was also shown to have genome characteristics typical of EVs. Phylogenetic analysis of P1, 2C and 3CD aa indicated that SEV-gx can be classified as a distinct cluster in the EVs. All of this evidence demonstrates SEV-gx is a novel species (tentatively named EV-K) in the EV genus, which contributes to our understanding of the genetic diversity and evolution of EVs. Further studies are needed to investigate the potential pathogenicity of SEV-gx in NHPs and humans.

Indexed as

AnimalsChinaEnterovirusEnterovirus InfectionsEvolution, MolecularFecesGenetic VariationGenome, ViralHumansMacaca mulattaMetagenomicsMonkey DiseasesNucleic Acid ConformationPhylogenyRNA, ViralSequence Analysis, RNARNA, ViralViral Structural Proteins

Identifiers

PMID27329349
PMCPMC4916455
OpenAlexW2467972084

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.