ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2016
Trends in ExPEC serogroups in the UK and their significance.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global Extraintestinal Pathogenic Escherichia coli (ExPEC) Lineages.Clinical microbiology reviews · 2019Pooled it
- A retrospective global study of the prevalence of O-serotypes of invasiveEpidemiology and infection · 2025Observational
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- Epidemiology, Virulence and Antimicrobial Resistance ofMicroorganisms · 2024Article
- Synergy between Group 2 capsules and lipopolysaccharide underpins serum resistance in extra-intestinal pathogenicMicrobiology (Reading, England) · 2024Article
- A randomized phase 1/2a trial of ExPEC10V vaccine in adults with a history of UTI.NPJ vaccines · 2024Article
- OXA-48-Producing Uropathogenic Escherichia coli Sequence Type 127, the Netherlands, 2015-2022.Emerging infectious diseases · 2023Article
- Uropathogenic Escherichia coli population structure and antimicrobial susceptibility in Norfolk, UK.The Journal of antimicrobial chemotherapy · 2023Article
- Global Distribution of O Serotypes and Antibiotic Resistance in Extraintestinal Pathogenic Escherichia coli Collected From the Blood of Patients With Bacteremia Across Multiple Surveillance Studies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Semisynthetic Glycoconjugate Vaccine Candidates againstJACS Au · 2022Article
- Close genetic linkage between human and companion animal extraintestinal pathogenicCurrent research in microbial sciences · 2022Article
- The Darkest Place Is under the Candlestick-Healthy Urogenital Tract as a Source of Worldwide Disseminated Extraintestinal PathogenicMicroorganisms · 2021Article
- Defining nosocomial transmission ofThe Lancet. Microbe · 2021Observational
- Molecular epidemiology of antimicrobial resistant microorganisms in the 21th century: a review of the literature.Acta bio-medica : Atenei Parmensis · 2020Review
- Molecular characterization of avian pathogenic Escherichia coli from broiler chickens with colibacillosis.Poultry science · 2020Article
- Article
- Article
- Genomic Epidemiology of Major Extraintestinal PathogenicOpen forum infectious diseases · 2019Article
- Pneumonia-Specific Escherichia coli with Distinct Phylogenetic and Virulence Profiles, France, 2012-2014.Emerging infectious diseases · 2019Article
- Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Extra-intestinal pathogenic Escherichia coli are a significant cause of urinary tract infection and bacteraemia within the UK. We sought to identify the serogroups of 658 E. coli isolates collected in the UK between January 2011 and March 2012, to better understand the ExPEC population and understand the relevance of serogroups in this pathotype. Isolates were typed and serogroup identified using established phenotypic and molecular methods. Sixty-two serogroups were identified; 54 among urinary isolates and 35 among bloodstream isolates. However, serogroups O25, O6, and O2 dominated both infection types. These serogroups were linked to the major ExPEC STs as follows: ST131-O25, ST73-O6, ST127-O6, and ST95-O2. The serogroup data from this study have increased our understanding of the ExPEC population in the UK, but also highlighted key ST-serogroup relationships within the major ExPEC clones. These data can be used to guide vaccine design and in the development of laboratory diagnostic tests targeting the ExPEC population.
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