Evidence map›Paper›PMID 27329159›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2016

Advanced abdominal imaging with dual energy CT is feasible without increasing radiation dose.

Monika Uhrig, David Simons, Marc Kachelrieß, Francesco Pisana, Stefan Kuchenbecker, Heinz-Peter Schlemmer

Abstract read
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Virtual non-calcium dual-energy CT: clinical applications.European radiology experimental · 2021
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. What scans we will read: imaging instrumentation trends in clinical oncology.Cancer imaging : the official publication of the International Cancer Imaging Society · 2020
    Review
  18. Article
  19. Article
  20. Bone Marrow Adipose Tissue Quantification by Imaging.Current osteoporosis reports · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Monika UhrigDepartment of Radiology, German Cancer Research Center (DKFZ) Heidelberg, Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany. m.uhrig@dkfz.de.
David SimonsDepartment of Radiology, German Cancer Research Center (DKFZ) Heidelberg, Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.
Marc KachelrießDepartment of Medical Physics in Oncology, Division of X-Ray Imaging and Computed Tomography, German Cancer Research Center (DKFZ) Heidelberg, Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.
Francesco PisanaDepartment of Medical Physics in Oncology, Division of X-Ray Imaging and Computed Tomography, German Cancer Research Center (DKFZ) Heidelberg, Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.
Stefan KuchenbeckerDepartment of Medical Physics in Oncology, Division of X-Ray Imaging and Computed Tomography, German Cancer Research Center (DKFZ) Heidelberg, Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.
Heinz-Peter SchlemmerDepartment of Radiology, German Cancer Research Center (DKFZ) Heidelberg, Im Neuenheimer Feld 280, D-69120, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDual energy CT (DECT) has proven its potential in oncological imaging. Considering the repeated follow-up examinations, radiation dose should not exceed conventional single energy CT (SECT). Comparison studies on the same scanner with a large number of patients, considering patient geometries and image quality, and exploiting full potential of SECT dose reduction are rare. Purpose of this retrospective study was to compare dose of dual source DECT versus dose-optimized SECT abdominal imaging in clinical routine.

methodsOne hundred patients (62y (±14)) had either contrast-enhanced SECT including automatic voltage control (44) or DECT (56). CT dose index (CTDIvol), size-specific dose-estimate (SSDE) and dose-length product (DLP) were reported. Image noise (SD) was recorded as mean of three ROIs placed in subcutaneous fat and normalized to dose by [Formula: see text] . For dose-normalized contrast-to-noise ratio (CNRD), mean attenuation of psoas muscle (CTmuscle) and subcutaneous fat (CTfat) were compared by CNRD = (CTmuscle - CTfat)/SDn. Statistical significance was tested with two-sided t-test (α = 0.05).

resultsThere was no significant difference (p < 0.05) between DECT and SECT: Mean CTDIvol was 14.2 mGy (±3.9) (DECT) and 14.3 mGy (±4.5) (SECT). Mean DLP was 680 mGy*cm (±220) (DECT) and 665 mGy*cm (±231) (SECT). Mean SSDE was 15.7 mGy (±1.9) (DECT) and 16.1 mGy (±2.5) (SECT). Mean SDn was 42.2 (±13.9) HU [Formula: see text] (DECT) and 47.8 (±14.9) HU [Formula: see text] (SECT). Mean CNRD was 3.9 (±1.3) [Formula: see text]. (DECT) and 4.0 (±1.3) [Formula: see text] (SECT).

conclusionAbdominal DECT is feasible without increasing radiation dose or deteriorating image quality, even compared to dose-optimized SECT including automatic voltage control. Thus DECT can contribute to sophisticated oncological imaging without dose penalty.

Indexed as

AbdomenAbdominal NeoplasmsDose-Response Relationship, RadiationFemaleHumansMaleMiddle AgedRadiation DosageReproducibility of ResultsRetrospective StudiesTomography, X-Ray ComputedAbdominal imagingDual energy CTOncological imagingRadiation dose

Identifiers

PMID27329159
PMCPMC4915171

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.