ArticleScientific reports2016
Biochemical basis of synergism between pathogenic fungus Metarhizium anisopliae and insecticide chlorantraniliprole in Locusta migratoria (Meyen).
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.
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- In Vitro Response of Two Strains ofJournal of fungi (Basel, Switzerland) · 2024Article
- Improved control of Trialeurodes vaporariorum using mixture combinations of entomopathogenic fungi and the chemical insecticide spiromesifen.Scientific reports · 2024Article
- Toxicological and Biochemical Description of Synergism ofJournal of fungi (Basel, Switzerland) · 2022Article
- Compatibility and synergistic interactions of fungi, Metarhizium anisopliae, and insecticide combinations against the cotton aphid, Aphis gossypii Glover (Hemiptera: Aphididae).Scientific reports · 2022Article
- Screening and evaluation of different algal extracts and prospects for controlling the disease vector mosquitoSaudi journal of biological sciences · 2022Article
- Mortality, Enzymatic Antioxidant Activity and Gene Expression of Cabbage Aphid (Frontiers in physiology · 2022Article
- Acaricidal and pathogenic effects of the entomopathogenic fungus Beauveria bassiana on engorged females of the fowl tick, Argas persicus (Argasidae).Experimental & applied acarology · 2021Article
- Synergistic Interaction between the Entomopathogenic FungusJournal of fungi (Basel, Switzerland) · 2021Article
- Aspergillus flavus induced oxidative stress and immunosuppressive activity in Spodoptera litura as well as safety for mammals.BMC microbiology · 2021Article
- Dynamic changes of transcriptome of fifth-instar3 Biotech · 2021Article
- Fungus Metarhizium robertsii and neurotoxic insecticide affect gut immunity and microbiota in Colorado potato beetles.Scientific reports · 2021Article
- Synergy in Efficacy ofFrontiers in physiology · 2021Article
- Toxicity and Biological Effects ofInsects · 2020Article
- Schizophyllum commune induced oxidative stress and immunosuppressive activity in Spodoptera litura.BMC microbiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We challenged Locusta migratoria (Meyen) grasshoppers with simultaneous doses of both the insecticide chlorantraniliprole and the fungal pathogen, Metarhizium anisopliae. Our results showed synergistic and antagonistic effects on host mortality and enzyme activities. To elucidate the biochemical mechanisms that underlie detoxification and pathogen-immune responses in insects, we monitored the activities of 10 enzymes. After administration of insecticide and fungus, activities of glutathione-S-transferase (GST), general esterases (ESTs) and phenol oxidase (PO) decreased in the insect during the initial time period, whereas those of aryl acylamidase (AA) and chitinase (CHI) increased during the initial period and that of acetylcholinesterase (AChE) increased during a later time period. Activities of superoxide dismutase (SOD), catalase (CAT) and peroxidase (POD) decreased at a later time period post treatment. Interestingly, treatment with chlorantraniliprole and M. anisopliae relieved the convulsions that normally accompany M. anisopliae infection. We speculate that locust mortality increased as a result of synergism via a mechanism related to Ca(2+) disruption in the host. Our study illuminates the biochemical mechanisms involved in insect immunity to xenobiotics and pathogens as well as the mechanisms by which these factors disrupt host homeostasis and induce death. We expect this knowledge to lead to more effective pest control.
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