Evidence map›Paper›PMID 27328903›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2016

Belatacept Conversion in an HIV-Positive Kidney Transplant Recipient With Prolonged Delayed Graft Function.

Z Ebcioglu, C Liu, R Shapiro, M Rana, F Salem, S Florman, S Huprikar, V Nair

Open access · hybridAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Challenges of kidney transplantation in HIV positive recipients.Translational andrology and urology · 2019
    Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Z EbciogluRecanati/Miller Transplantation Institute, The Mount Sinai Medical Center, New York, NY.
C LiuRecanati/Miller Transplantation Institute, The Mount Sinai Medical Center, New York, NY.
R ShapiroRecanati/Miller Transplantation Institute, The Mount Sinai Medical Center, New York, NY.
M RanaDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
F SalemDepartment of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY.
S FlormanRecanati/Miller Transplantation Institute, The Mount Sinai Medical Center, New York, NY.
S HuprikarDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
V NairRecanati/Miller Transplantation Institute, The Mount Sinai Medical Center, New York, NY. vinay.nair@mountsinai.org.
Icahn School of Medicine at Mount Sinai · USMount Sinai Hospital · USMount Sinai Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report an HIV-positive renal transplant recipient with delayed graft function who was converted from tacrolimus to belatacept in an attempt to improve renal function. The patient had kidney biopsies at 4 and 8 weeks posttransplant that revealed acute tubular necrosis and mild fibrosis. After 14 weeks of delayed function, belatacept was initiated and tacrolimus was weaned off. Shortly after discontinuing tacrolimus, renal function began to improve. The patient was able to discontinue dialysis 21 weeks posttransplant. HIV viral load was undetectable at last follow-up. To our knowledge, this is the first report of belatacept use in a patient with HIV.

Indexed as

Kidney TransplantationAbataceptDelayed Graft FunctionGlomerular Filtration RateGraft RejectionGraft SurvivalHIV-1HIV InfectionsHumansImmunosuppressive AgentsKidney Failure, ChronicKidney Function TestsMaleMiddle AgedPrognosisRisk FactorsAbataceptImmunosuppressive Agentsclinical research/practicedelayed graft function (DGF)fusion proteins and monoclonal antibodies: belataceptimmunosuppressantimmunosuppression/immune modulationimmunosuppressive regimensinfection and infectious agentsinfectious diseasekidney transplantation/nephrologymaintenanceviral: human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS)

Identifiers

PMID27328903
OpenAlexW2467657736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.