Evidence map›Paper›PMID 27326927›Full record

ArticleDevelopmental cell2016

Nucleus to Mitochondria: Lost in Transcription, Found in Translation.

Julie St-Pierre, Ivan Topisirovic

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Perturbation of mitochondrial CaStress biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Julie St-PierreGoodman Cancer Research Centre, McGill University, Montréal, QC H3A 1A3, Canada; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada. Electronic address: julie.st-pierre@mcgill.ca.
Ivan TopisirovicDepartment of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada; Department of Oncology, McGill University, Montreal, QC H3A 1A3, Canada; Department of Experimental Medicine, McGill University, Montreal, QC H3A 1A3, Canada; Lady Davis Institute, SMBD JGH, McGill University, Montréal, QC H3T 1E2, Canada. Electronic address: ivan.topisirovic@mcgill.ca.
McGill University · CAMcGill University Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial genes reside in the nucleus and mitochondria. In a recent paper in Nature, Couvillion et al. (2016) describe their development of a "mitoribosome profiling" approach and demonstrate that changes in expression of nuclear- and mitochondrial-encoded genes are coordinated at the level of translation during metabolic adaptation to fuel source changes.

Indexed as

Protein BiosynthesisTranscription, GeneticAnimalsBiological EvolutionCell NucleusHumansMitochondriaModels, BiologicalMitochondrial biogenesismRNA translationRibosome profiling

Identifiers

PMID27326927
OpenAlexW2463792537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.