Evidence map›Paper›PMID 27326714›Full record

ArticleCurrent biology : CB2016

Innate Immunity: ER Stress Recruits NOD1 and NOD2 for Delivery of Inflammation.

Roberta Caruso, Gabriel Núñez

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Frontiers in cellular and infection microbiology · 2024
    Review
  3. Article
  4. Inflammatory Mechanism ofInternational journal of molecular sciences · 2022
    Review
  5. Review
  6. Review
  7. Article
  8. NOD2 and inflammation: current insights.Journal of inflammation research · 2018
    Review
  9. Lytic transglycosylases: concinnity in concision of the bacterial cell wall.Critical reviews in biochemistry and molecular biology · 2017
    Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Roberta CarusoDepartment of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
Gabriel NúñezDepartment of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address: gabriel.nunez@umich.edu.
University of Michigan–Ann Arbor · US

Funding

Nod2: A Susceptibility Gene for Crohn's DiseaseR01DK061707 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NUNEZ, GABRIEL · 2002 to 2017
$4.7M
6 · The paper itself

Abstract

NOD1 and NOD2, two members of the intracellular NOD-like receptor family, sense bacterial peptidoglycan-derived fragments and induce pro-inflammatory responses. Recent work provides evidence for a role for NOD1/NOD2 signaling in mediating ER-stress-induced inflammatory responses via a peptidoglycan-independent mechanism.

Indexed as

Endoplasmic Reticulum StressImmunity, InnateBrucella abortusInflammationNod1 Signaling Adaptor ProteinNod2 Signaling Adaptor ProteinNod1 Signaling Adaptor ProteinNod2 Signaling Adaptor Protein

Identifiers

PMID27326714
OpenAlexW2474739307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.