Evidence map›Paper›PMID 27326387›Full record

ArticleCurrent molecular biology reports2016

Cell Mechanosensitivity is Enabled by the LINC Nuclear Complex.

Gunes Uzer, Clinton T Rubin, Janet Rubin

Open access · bronzeAbstract read
In one paragraph

Article in Current molecular biology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The LINC Complex Regulates Tendon Elastic Modulus, Collagen Crimp, and Lateral Expansion During Early Postnatal Development.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  5. Article
  6. Cellular and Nuclear Forces: An Overview.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. DYT-Frontiers in neuroscience · 2023
    Review
  12. Single Cell in a Gravity Field.Life (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gunes UzerDepartment of Medicine, University of North Carolina, Chapel Hill, NC 27599.
Clinton T RubinDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY, 11794.
Janet RubinDepartment of Medicine, University of North Carolina, Chapel Hill, NC 27599.
University of North Carolina at Chapel Hill · USStony Brook University · US

Funding

Mechanical regulation of cytoskeleton guides beta-catenin effect on MSC fateR01AR066616 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUBIN, JANET E · 2015 to 2019
$1.7M
Mechanical Control of Mesenchymal Stem Cell Lineage AllocationR01AR056655 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUBIN, JANET E · 2010 to 2014
$1.4M
Harnessing mechanical signals to control mesenchymal stem cell fateR01EB014351 · NIBIB · STATE UNIVERSITY NEW YORK STONY BROOK · PI JUDEX, STEFAN, RUBIN, CLINTON T · 2012 to 2014
$1.0M
NIAMS NIH HHS R01 AR056655NIAMS NIH HHS R01 AR066616NIBIB NIH HHS R01 EB014351
6 · The paper itself

Abstract

Mechanoresponses in mesenchymal stem cells (MSCs) guide both differentiation and function. In this review, we focus on advances in0 our understanding of how the cytoplasmic cytoskeleton, nuclear envelope and nucleoskeleton, which are connected via LINC (

Indexed as

ActinBoneDifferentiationEmerinFAKFatLaminNesprinNucleoskeletonSun

Identifiers

PMID27326387
PMCPMC4912015
OpenAlexW2341285447

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.